MORNING AND NOCTURNAL SERUM MELATONIN LEVELS IN THE PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND HEALTHY CONTROLS

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KHALEGHIPOUR S.; AHADE H.; ENAYATE M.; PASHA G.; NADERY F.; MASJEDI M.

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Journal: JOURNAL OF SOCIAL PSYCHOLOGY (NEW FINDINGS IN PSYCHOLOGY) Year:2011 | Volume:6 | Issue:20 Page(s): 119-129

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Title

MORNING AND NOCTURNAL SERUM MELATONIN LEVELS IN THE PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND HEALTHY CONTROLS

Author(s)

Keywords

MAJOR DEPRESSIVE DISORDERQ2

MELATONINQ2

SERUMQ2

CIRCADIAN RHYTHMQ2

Abstract

The pineal gland is an adaptive organ, which produces MELATONIN. MELATONIN regulates the biological rhythms precisely, and in turn, biological rhythms regulate the brain haemostasis. Since deregulation in the MELATONIN rhythm is a probable cause for depression disorder, this thesis aimed to measure the SERUM MELATONIN levels in the patients with major depression disorder (MDD) and healthy controls. This study of causal-comparative was a type of case-control. The sample consisted of 42 patients with MDD and 50 healthy controls. Blood samples were drawn to measure the morning and nocturnal SERUM MELATONIN levels, using the ELISA method. Morning SERUM MELATONIN levels of the patients with MDD were significantly higher than those of controls. Nocturnal SERUM MELATONIN levels of the patients with MDD were lower than those of the controls. Nocturnal MELATONIN levels of the females were lower than those of the males. The findings suggest that the peak time of MELATONIN in the patients with MDD is accompanied by delay.

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References

STUDY OF THE EFFECT OF MELATONIN ON WATER IMMERSION STRESS- INDUCED GASTRIC LESION

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APA: Copy

KHALEGHIPOUR, S., AHADE, H., ENAYATE, M., PASHA, G., NADERY, F., & MASJEDI, M.. (2011). MORNING AND NOCTURNAL SERUM MELATONIN LEVELS IN THE PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND HEALTHY CONTROLS. JOURNAL OF SOCIAL PSYCHOLOGY (NEW FINDINGS IN PSYCHOLOGY), 6(20), 119-129. SID. https://sid.ir/paper/175032/en

Vancouver: Copy

KHALEGHIPOUR S., AHADE H., ENAYATE M., PASHA G., NADERY F., MASJEDI M.. MORNING AND NOCTURNAL SERUM MELATONIN LEVELS IN THE PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND HEALTHY CONTROLS. JOURNAL OF SOCIAL PSYCHOLOGY (NEW FINDINGS IN PSYCHOLOGY)[Internet]. 2011;6(20):119-129. Available from: https://sid.ir/paper/175032/en

IEEE: Copy

S. KHALEGHIPOUR, H. AHADE, M. ENAYATE, G. PASHA, F. NADERY, and M. MASJEDI, “MORNING AND NOCTURNAL SERUM MELATONIN LEVELS IN THE PATIENTS WITH MAJOR DEPRESSIVE DISORDER AND HEALTHY CONTROLS,” JOURNAL OF SOCIAL PSYCHOLOGY (NEW FINDINGS IN PSYCHOLOGY), vol. 6, no. 20, pp. 119–129, 2011, [Online]. Available: https://sid.ir/paper/175032/en

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