STUDY OF RELATIONSHIP BETWEEN LEPTIN AND RISK FACTORS FOR CORONARY HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON DIABETIC CONTROLS

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BAGHERI A.A.H.; OLAMAEI R.; KHOSRAVI AHMAD; KHOSRAVI M.

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Journal: Avicenna Journal of Clinical Medicine Year:2006 | Volume:12 | Issue:4 (SN 38) Page(s): 17-22

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Title

STUDY OF RELATIONSHIP BETWEEN LEPTIN AND RISK FACTORS FOR CORONARY HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON DIABETIC CONTROLS

Author(s)

BAGHERI A.A.H. | OLAMAEI R. | KHOSRAVI AHMAD | KHOSRAVI M. | Issue Writer Certificate

Keywords

BODY MASS INDEXQ3

CORONARY DISEASEQ3

DIABETES MELLITUSQ2

LEPTINQ3

Abstract

Introduction & Objective: LEPTIN is considered to play an important role in the regulation of body weight and metabolism. Many studies have shown an association between BMI and LEPTIN concentration. Our study compares the relationship between plasma LEPTIN levels and risk factors for CHD in patients with type 2 diabetes and non-diabetic controls. Materials & Methods: A total of 88 patients without diabetes (group A) were compared with 17 diabetic subjects (group B). Patients with CHD; according to myocardial perfusion scan results, renal, thyroid and hepatic disorders were excluded from the study. After a 12-hours overnight fast, blood samples were obtained. Plasma was immediately separated for laboratory measurements: Plasma LEPTIN levels were measured with radioimmunoassay (RIA) kit.Results: The mean age for 88 non-diabetic subjects and 17 diabetic patients didn't have differences. Frequency of smoking and BMI mean score were significantly higher in diabetic patients. There were no differences in LEPTIN levels in two groups. A close relationship between BMI and LEPTIN levels was observed.Conclusion: LEPTIN concentration didn't show correlation with CHD risk factors except for BMI in diabetic and nondiabetic subjects.

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APA: Copy

BAGHERI, A.A.H., OLAMAEI, R., KHOSRAVI, AHMAD, & KHOSRAVI, M.. (2006). STUDY OF RELATIONSHIP BETWEEN LEPTIN AND RISK FACTORS FOR CORONARY HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON DIABETIC CONTROLS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 12(4 (SN 38)), 17-22. SID. https://sid.ir/paper/17854/en

Vancouver: Copy

BAGHERI A.A.H., OLAMAEI R., KHOSRAVI AHMAD, KHOSRAVI M.. STUDY OF RELATIONSHIP BETWEEN LEPTIN AND RISK FACTORS FOR CORONARY HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON DIABETIC CONTROLS. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2006;12(4 (SN 38)):17-22. Available from: https://sid.ir/paper/17854/en

IEEE: Copy

A.A.H. BAGHERI, R. OLAMAEI, AHMAD KHOSRAVI, and M. KHOSRAVI, “STUDY OF RELATIONSHIP BETWEEN LEPTIN AND RISK FACTORS FOR CORONARY HEART DISEASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON DIABETIC CONTROLS,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 12, no. 4 (SN 38), pp. 17–22, 2006, [Online]. Available: https://sid.ir/paper/17854/en

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