REPORT OF LONG-TERM OUT COMES OF SURGERIES ON 41 PATIENTS WITH MEDULLOBLASTOMA OVER TWENTY-THREE YEARS

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ZALI A.R.; MOHSENI MOSTAFA; TABATABAI S.M.; SEDIGHI A.; SEDIGHI AMIR SAEID; TABATABAEIFAR S.M.

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Journal: Researcher Bulletin of Medical Sciences Year:2006 | Volume:11 | Issue:4 (52) Page(s): 205-210

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Title

REPORT OF LONG-TERM OUT COMES OF SURGERIES ON 41 PATIENTS WITH MEDULLOBLASTOMA OVER TWENTY-THREE YEARS

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Keywords

MEDULLOBLASTOMAQ3

EPIDEMIOLOGYQ3

VP SHUNTQ3

RADIOTHERAPYQ3

Abstract

Background: MEDULLOBLASTOMA which is classified as a primitive neuroectodermal tumor in WHO classification primarily affects pediatric population& constitutes about 25 percent of all intracranial neoplasms in this age group. Epidemiological characteristics of this neoplasm are somehow different in developing countries, as diagnosis is usually made in advanced stages of the disease.Results of surgery on 41 patients and outcome of adjuvant therapy between 1982 and 2005 have been reported.Materials & Methods: Results of treatment in 41 patients with long term follow-up are presented. Signs and symptoms, imaging, removal degree, management of hydrocephaly and shunt insertion policy were reviewed as well as clinical outcomes and results of adjuvant therapy, also discussed are the complications and mortality in this series. Resection was evaluated with post operative contrast enhanced compute tomography.Results: This was a study based on medical data of 41 patients with a 23 year follow-up. Twenty seven (66%) were male and 14 (34%) were female. When operated the mean age was 10.8 y (range between 6m and 32 y). Patients were followed between 6 and 261 months (mean f/u was 52m). 61 percent had disease free survival.Conclusions: VP SHUNT was used more frequently in our series which is probably due to late diagnosis in developing countries and our policy for precraniotomy shunting. RADIOTHERAPY plays a major role in controlling the disease in cases where total resection leads to neurological deficit.

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APA: Copy

ZALI, A.R., MOHSENI, MOSTAFA, TABATABAI, S.M., SEDIGHI, A., SEDIGHI, AMIR SAEID, & TABATABAEIFAR, S.M.. (2006). REPORT OF LONG-TERM OUT COMES OF SURGERIES ON 41 PATIENTS WITH MEDULLOBLASTOMA OVER TWENTY-THREE YEARS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 11(4 (52)), 205-210. SID. https://sid.ir/paper/18187/en

Vancouver: Copy

ZALI A.R., MOHSENI MOSTAFA, TABATABAI S.M., SEDIGHI A., SEDIGHI AMIR SAEID, TABATABAEIFAR S.M.. REPORT OF LONG-TERM OUT COMES OF SURGERIES ON 41 PATIENTS WITH MEDULLOBLASTOMA OVER TWENTY-THREE YEARS. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2006;11(4 (52)):205-210. Available from: https://sid.ir/paper/18187/en

IEEE: Copy

A.R. ZALI, MOSTAFA MOHSENI, S.M. TABATABAI, A. SEDIGHI, AMIR SAEID SEDIGHI, and S.M. TABATABAEIFAR, “REPORT OF LONG-TERM OUT COMES OF SURGERIES ON 41 PATIENTS WITH MEDULLOBLASTOMA OVER TWENTY-THREE YEARS,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 11, no. 4 (52), pp. 205–210, 2006, [Online]. Available: https://sid.ir/paper/18187/en

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