ANTI HEPATITIS E VIRUS ANTIBODY IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN

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KHOUSHBATEN M.; ZALI MOHAMMAD REZA; TAREMI M.; GACHKAR L.; ARGANI H.; MAHMOUD ARABI S.M.; ABEDI AZAR S.; SHAHNAZI T.; ZOU ALFAGHARIAN K.

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Journal: Researcher Bulletin of Medical Sciences Year:2005 | Volume:9 | Issue:6 (42) Page(s): 323-326

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Title

ANTI HEPATITIS E VIRUS ANTIBODY IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN

Author(s)

Keywords

HEPATITIS EQ4

HEMODIALYSIS PATIENTSQ4

IGG ANTI-HEYQ3

IRANQ3

Abstract

Background: The HEPATITIS E virus (HEV) has a global distribution and is known to have caused large waterborne epidemics of icteric hepatitis. Transmission is generally via the fecal oral route. Some reports have suggested parenterally transmission of HEV. Anti-HEV prevalence data among chronic hemodialysis (HD) patients are few and given conflicting results.Materials and Methods: This cross-sectional study was conducted in August of 2004.We tested 324 chronic HD patients attending three different units in the city of Tabriz, in the northwestern part of IRAN, for anti-HEV antibody. A specific solid- phase enzyme-linked immunoassay (Diapro, Italy) was used.Results: The overall seroprevalence of HEPATITIS E was7.4% (95% CI: 4.6%-10.6%).The prevalence rate of HBV and HCV infection were 4.6% (95% CI: 2.3%-6.9%) and 20.4% (95% CI: 16%-24.8%) respectively. The seroprevalence of anti-HEV antibody among chronic HD patients was associated significantly with age. No statistically significant association was observed between HEV seropositivity and other variables. Conclusion: We observed high anti-HEV prevalence; there was no association between HEV and blood borne infections (HBV, HCV, HIV) in our HD patients; most anti -HEV positive patients we found were probably related to a local infection by HEV. This is the first report concerning seroepidemiology of HEV infection in a large cohort of chronic HD individuals in IRAN.

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APA: Copy

KHOUSHBATEN, M., ARGANI, H., ABEDI AZAR, S., ZALI, MOHAMMAD REZA, TAREMI, M., MAHMOUD ARABI, S.M., ZOU ALFAGHARIAN, K., GACHKAR, L., & SHAHNAZI, T.. (2005). ANTI HEPATITIS E VIRUS ANTIBODY IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), 9(6 (42)), 323-326. SID. https://sid.ir/paper/18213/en

Vancouver: Copy

KHOUSHBATEN M., ARGANI H., ABEDI AZAR S., ZALI MOHAMMAD REZA, TAREMI M., MAHMOUD ARABI S.M., ZOU ALFAGHARIAN K., GACHKAR L., SHAHNAZI T.. ANTI HEPATITIS E VIRUS ANTIBODY IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN. RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH)[Internet]. 2005;9(6 (42)):323-326. Available from: https://sid.ir/paper/18213/en

IEEE: Copy

M. KHOUSHBATEN, H. ARGANI, S. ABEDI AZAR, MOHAMMAD REZA ZALI, M. TAREMI, S.M. MAHMOUD ARABI, K. ZOU ALFAGHARIAN, L. GACHKAR, and T. SHAHNAZI, “ANTI HEPATITIS E VIRUS ANTIBODY IN HEMODIALYSIS PATIENTS: A SEROEPIDEMIOLOGICAL SURVEY IN IRAN,” RESEARCHER BULLETIN OF MEDICAL SCIENCES (PEJOUHANDEH), vol. 9, no. 6 (42), pp. 323–326, 2005, [Online]. Available: https://sid.ir/paper/18213/en

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