Integrated radiologic diagnosis of pulmonary artery intimal sarcoma: Report of three cases and literature review

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Fu X.; Zhao J.; Liu Q.; Jia J.; Wang M.

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Journal Paper

Paper Information

Journal: INTERNATIONAL JOURNAL OF RADIATION RESEARCH Year:2025 | Volume:23 | Issue:2 Page(s): 497-502

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Information Journal Paper

Title

Integrated radiologic diagnosis of pulmonary artery intimal sarcoma: Report of three cases and literature review

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Keywords

PAIS

endarterectomy

computed tomography angioplasty.

Abstract

Background: Pulmonary artery intimal sarcoma (PAIS), a rare malignancy arising primarily within the pulmonary artery's intimal layer, exhibits an estimated prevalence ranging from 0.001% to 0.003%. Due to overlapping clinical manifestations and imaging characteristics, PAIS is frequently mistaken for acute or chronic pulmonary thromboembolism. Tissue biopsy remains the authoritative method for establishing diagnosis. Regarding therapy, surgery is the principal approach, and undertaking thorough surgical resection alongside endarterectomy yields improved survival outcomes. Case Presentations: This study presents three cases of PAIS, analyzing their radiological characteristics, pathological findings, and therapeutic approaches. A comprehensive review of the literature on this condition is also provided. Conclusion: Timely detection proves paramount and can significantly enhance patient prognosis. Complete surgical resection is pivotal for improving prognosis, and multidisciplinary collaboration (e.g., radiology, pathology, and thoracic surgery) plays a vital role in formulating precise diagnostic and therapeutic strategies.

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