THE STUDY OF THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF ALFALFA SHOOTS ON MEDICAGO SATIVA IN THE TREATMENT OF ACETIC ACID INDUCED GASTRIC ULCER IN RATS

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SAMARI M.; RAHNEMA M.; NASIRI SEMNANI SH.

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Journal Paper

Paper Information

Journal: JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES) Year:2014 | Volume:7 | Issue:2 (25) Page(s): 59-71

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Title

THE STUDY OF THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF ALFALFA SHOOTS ON MEDICAGO SATIVA IN THE TREATMENT OF ACETIC ACID INDUCED GASTRIC ULCER IN RATS

Author(s)

SAMARI M. | RAHNEMA M. | NASIRI SEMNANI SH. | Issue Writer Certificate

Keywords

MEDICAGO SATIVA EXTRACTQ2

GASTRIC ULCERQ2

BLOOD INDICEQ1

Abstract

Inroduction & Objective: Peptic ulcer, from histological point is known as mucosal necrosis factor. The purpose of this study was to investigate the effect of Alfalfa hydroalcoholic vegetive arial organs extract on GASTRIC ULCER induced by acetic acid in Rat.Material and Methods: In this experimental study, 60 wistar rats weighting approximately (200-250g) were randomly divided into 4 groups; control, sham (normal salin), experiment 1 (extract of dose 250 mg/kg body weight) and experiment 2 (extract of dose 500 mg/kg body weight). Rats were deprived of food and then underwent surgery and gastric was by injecting 60% acetic acid after 4,7,10,14 days gavage, the rats' stomach out and then measuring the wound and fixed with 10% formalin, the passage of the tissue section was stained And the number of neutrophils, macrophages and fibroblasts were counted.Results: Results showed that the hydroalcoholic extract of Alfalfa caused a significant increase in GASTRIC ULCER healing in experimental groups 1 and 2 (P<0.05). Average number of neutrophils and macrophages during the fourth day and average number of fibroblast in the fourth and seventh days showed a significant increase and in other days had decreased compared to the sham and control groups (P<0.05).Conclusion: Alfalfa hydroalcoholic vegetive arial organs extract is effective in the treatment of peptic ulcer induced by acetic acid.

Cites

THE EFFECT OF DIFFERENT DOSES OF ALCOHOLIC EXTRACT OF ALFALFA ON THE CONTROL OF OXIDATIVE STRESS BY NICOTINE IN THE OVARIES OF FEMALE RATS

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APA: Copy

SAMARI, M., RAHNEMA, M., & NASIRI SEMNANI, SH.. (2014). THE STUDY OF THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF ALFALFA SHOOTS ON MEDICAGO SATIVA IN THE TREATMENT OF ACETIC ACID INDUCED GASTRIC ULCER IN RATS. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), 7(2 (25)), 59-71. SID. https://sid.ir/paper/191630/en

Vancouver: Copy

SAMARI M., RAHNEMA M., NASIRI SEMNANI SH.. THE STUDY OF THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF ALFALFA SHOOTS ON MEDICAGO SATIVA IN THE TREATMENT OF ACETIC ACID INDUCED GASTRIC ULCER IN RATS. JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES)[Internet]. 2014;7(2 (25)):59-71. Available from: https://sid.ir/paper/191630/en

IEEE: Copy

M. SAMARI, M. RAHNEMA, and SH. NASIRI SEMNANI, “THE STUDY OF THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF ALFALFA SHOOTS ON MEDICAGO SATIVA IN THE TREATMENT OF ACETIC ACID INDUCED GASTRIC ULCER IN RATS,” JOURNAL OF ANIMAL PHYSIOLOGY AND DEVELOPMENT (QUARTERLY JOURNAL OF BIOLOGICAL SCIENCES), vol. 7, no. 2 (25), pp. 59–71, 2014, [Online]. Available: https://sid.ir/paper/191630/en

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