DETECTION OF BLAVIM GENE AMONG IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM BURN WOUNDS FROM TEHRAN SHAHID MOTAHARI HOSPITAL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAMALI SH.; BAHAR M.A.; HOUSHMAND S.M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MICROBIOLOGY KNOWLEDGE Year:2009 | Volume:1 | Issue:1 Page(s): 19-25

Download Full-Text

Persian Verion

View:

1,351

Download:

Cites:

Information Journal Paper

Title

DETECTION OF BLAVIM GENE AMONG IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM BURN WOUNDS FROM TEHRAN SHAHID MOTAHARI HOSPITAL

Author(s)

JAMALI SH. | BAHAR M.A. | HOUSHMAND S.M. | Issue Writer Certificate

Keywords

PSEUDOMONAS AERUGINOSAQ4

METALLO-γ-LACTAMASEQ4

ANTIMICROBIAL RESISTANT AND BURN WOUNDQ4

Abstract

PSEUDOMONAS AERUGINOSA is one of the most common causes of nosocomial infections in Iran and the entire world. This organism is also the most common bacteria isolated from burn patients. Carbapenem are the best therapeutic choices for treatment of this organism. Among all these organisms metallo-b-lactamase-producing is becoming a severe therapeutic problem. This study was conducted to determine the drug susceptibility and detection of blaVIM and blaIMP metallo beta lactamase genes in P. aeruginosa isolated from burn wounds of patients. The antimicrobial activities of 10 common antimicrobial agents including carbapenem were tested against 186 clinical PSEUDOMONAS AERUGINOSA strains isolated by using a disk diffusion method and minimal inhibitory concentration (MIC) for Imipenem was determined. All imipenem-resistant isolates were screened for metallo-b-lactamase production by Imipenem-EDTA disk method and were subsequently screened by PCR to detect blaVIM & blaIMP genes. 115 (61.8%) of the isolates were resistant to imipenem have found. Of 115 imipenem-nonsusceptible isolates detected, 23 (20%) appeared to produce metallo-b-lactamase. Using PCR method, these isolates were positive for blaVIM genes, whereas none were positive for blaIMP genes. MBL-mediated imipenem resistance in PSEUDOMONAS AERUGINOSA is a cause of concern in the therapy of patients. This result suggests that surveillance programs should be applied to avoid the spread of these worrisome resistance genes.

Cites

No record.

References

Cite

APA: Copy

JAMALI, SH., BAHAR, M.A., & HOUSHMAND, S.M.. (2009). DETECTION OF BLA_VIM GENE AMONG IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM BURN WOUNDS FROM TEHRAN SHAHID MOTAHARI HOSPITAL. JOURNAL OF MICROBIOLOGY KNOWLEDGE, 1(1), 19-25. SID. https://sid.ir/paper/193216/en

Vancouver: Copy

JAMALI SH., BAHAR M.A., HOUSHMAND S.M.. DETECTION OF BLA_VIM GENE AMONG IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM BURN WOUNDS FROM TEHRAN SHAHID MOTAHARI HOSPITAL. JOURNAL OF MICROBIOLOGY KNOWLEDGE[Internet]. 2009;1(1):19-25. Available from: https://sid.ir/paper/193216/en

IEEE: Copy

SH. JAMALI, M.A. BAHAR, and S.M. HOUSHMAND, “DETECTION OF BLA_VIM GENE AMONG IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ISOLATED FROM BURN WOUNDS FROM TEHRAN SHAHID MOTAHARI HOSPITAL,” JOURNAL OF MICROBIOLOGY KNOWLEDGE, vol. 1, no. 1, pp. 19–25, 2009, [Online]. Available: https://sid.ir/paper/193216/en

Related Journal Papers