EVALUATION OF ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL OF CARVACROL ON STANDARD FLUCONAZOLE SENSITIVE AND RESISTANCE STRAINS OF CANDIDA ALBICANS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HOSEINI S.S.; ROUDBAR MOHAMMADI SH.; JOSHAGHANI H.R.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: MEDICAL LABORATORY JOURNAL Year:2012 | Volume:5 | Issue:2 Page(s): 28-33

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,285

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL OF CARVACROL ON STANDARD FLUCONAZOLE SENSITIVE AND RESISTANCE STRAINS OF CANDIDA ALBICANS

Author(s)

HOSEINI S.S. | ROUDBAR MOHAMMADI SH. | JOSHAGHANI H.R. | Issue Writer Certificate

Keywords

ANTIFUNGAL ACTIVITYQ2

CARVACROLQ2

CANDIDA ALBICANSQ3

FLUCONAZOLEQ2

Abstract

Background and objectives: CANDIDA ALBICANS is a human opportunistic fungus causing mucosal and systemic infections in immunocompromised individuals. There is evidence of increasing resistance to antifungal agents, thus it is necessary to search about new formulations for finding the antifungal agents. Some plants have antimicrobial properties due to presence of components such as polyphenols. We aimed at evaluating antifungal effects of CARVACROL essence, which is the main compound of essential oil of Thymus vulgaris, on standard FLUCONAZOLE sensitive and resistance strains of CANDIDA ALBICANS.Material and Methods: This study evaluated the anti-Candida activity of essential oil CARVACROL by means of Inhibitory zone diameter and Minimum Inhibitory Concentration (MIC), using Microdilution broth and Disc diffusion methods. To do this, Serial dilutions (10-100 μl) of essential oils were made in 96 well microtiter plates. The wells’ opacity was assessed by using a microtiter plate reader of solution. The Minimum Inhibitory Concentration (MIC) of essential oil CARVACROL and FLUCONAZOLE were measured by counting the number of colony in Dextro agar medium.Results: the minimum inhibitory concentration of CARVACROL essence in standard strains and FLUCONAZOLE-resistance CANDIDA ALBICANS are, respectively, 5.3 and 6.18μg/ml, and the Minimal Fungicide Concentration (MFC) are 10.61 and 12.3μg/ml. Inhibitory zone diameters are 45 and 35 millimeter for FLUCONAZOLE sensitive and resistance CANDIDA ALBICANS, respectively.Conclusion: the results show that essence of CARVACROL has suitable antifungal effects against standard strains and FLUCONAZOLE sensitive and resistance of CANDIDA ALBICANS. These herbal essences, after supplementary studies, possibly can be used for infections caused by Candidas.

Cites

COMPARISON THE INHIBITORY EFFECTS OF ESSENTIAL OIL OF THYMUS ERIOCALYX AND THYMUS KOTSCHYANUS WITH NYSTATIN ON CANDIDA ALBICANS GROWTH - IN VITRO STUDY

References

No record.

Cite

APA: Copy

HOSEINI, S.S., ROUDBAR MOHAMMADI, SH., & JOSHAGHANI, H.R.. (2012). EVALUATION OF ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL OF CARVACROL ON STANDARD FLUCONAZOLE SENSITIVE AND RESISTANCE STRAINS OF CANDIDA ALBICANS. MEDICAL LABORATORY JOURNAL, 5(2), 28-33. SID. https://sid.ir/paper/194797/en

Vancouver: Copy

HOSEINI S.S., ROUDBAR MOHAMMADI SH., JOSHAGHANI H.R.. EVALUATION OF ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL OF CARVACROL ON STANDARD FLUCONAZOLE SENSITIVE AND RESISTANCE STRAINS OF CANDIDA ALBICANS. MEDICAL LABORATORY JOURNAL[Internet]. 2012;5(2):28-33. Available from: https://sid.ir/paper/194797/en

IEEE: Copy

S.S. HOSEINI, SH. ROUDBAR MOHAMMADI, and H.R. JOSHAGHANI, “EVALUATION OF ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL OF CARVACROL ON STANDARD FLUCONAZOLE SENSITIVE AND RESISTANCE STRAINS OF CANDIDA ALBICANS,” MEDICAL LABORATORY JOURNAL, vol. 5, no. 2, pp. 28–33, 2012, [Online]. Available: https://sid.ir/paper/194797/en

Related Journal Papers