ASSESSMENT OF ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACT OF MYRTUS COMMUNIS (MYRTLE) LEAVES AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI

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JAVADIAN FERTESHTEH; BAGHERI GHOLAMREZA; SOHIL BAIGI GELAREH; SHAHI ZAHRA; MOHKAMI ZAYNAB

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Journal: JOURNAL OF ZABOL UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES (JOURNAL OF ROSTAMINEH) Year:2014 | Volume:6 | Issue:2 Page(s): 18-25

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Title

ASSESSMENT OF ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACT OF MYRTUS COMMUNIS (MYRTLE) LEAVES AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI

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ETHANOLIC EXTRACTQ2

ANTIBACTERIAL ACTIVITYQ2

MYRTUS COMMUNISQ2

URINARY TRACT INFECTIONQ2

E. COLIQ2

Abstract

Background: Considering the widespread dissemination of antibiotic resistance among human pathogenic bacteria, the search for new antimicrobial agents should be accelerated. In this study, we aimed to assess the antibacterial activities of ETHANOLIC EXTRACT of MYRTUS COMMUNIS (myrtle) leaves against multidrug-resistant Escherichia coli (abbreviated as E. COLI) strains isolated from URINARY TRACT INFECTIONs.Methods: M. communis extracts were obtained using rotary evaporator. In total, 30 strains of E. COLI, isolated from URINARY TRACT INFECTIONs, were analyzed at Zabol Hospital, Iran. Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) of plant extracts, at different concentrations, were determined using broth microdilution method. Susceptibility of the strains to antibiotics was determined using standard Kirby-Bauer disk diffusion method.Results: The results indicated that E. COLI isolates were resistant to agents including ceftazidime (26.6%) cefixime (40%), tetracycline (63.3%), and erythromycin (56.6%). The highest MIC value was observed in the ETHANOLIC EXTRACT of M. communis in 10 mg/ml concentration, with inhibition of 24 E coli. strains.Conclusion: The results showed the inhibitory activity of M. communis extract against multidrug-resistant E. COLI strains. Our study confirms the use of this essential oil as an antibacterial agent; however, further research is required before its therapeutic application.

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APA: Copy

JAVADIAN, FERTESHTEH, BAGHERI, GHOLAMREZA, SOHIL BAIGI, GELAREH, SHAHI, ZAHRA, & MOHKAMI, ZAYNAB. (2014). ASSESSMENT OF ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACT OF MYRTUS COMMUNIS (MYRTLE) LEAVES AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI. JOURNAL OF ZABOL UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES (JOURNAL OF ROSTAMINEH), 6(2), 18-25. SID. https://sid.ir/paper/203570/en

Vancouver: Copy

JAVADIAN FERTESHTEH, BAGHERI GHOLAMREZA, SOHIL BAIGI GELAREH, SHAHI ZAHRA, MOHKAMI ZAYNAB. ASSESSMENT OF ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACT OF MYRTUS COMMUNIS (MYRTLE) LEAVES AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI. JOURNAL OF ZABOL UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES (JOURNAL OF ROSTAMINEH)[Internet]. 2014;6(2):18-25. Available from: https://sid.ir/paper/203570/en

IEEE: Copy

FERTESHTEH JAVADIAN, GHOLAMREZA BAGHERI, GELAREH SOHIL BAIGI, ZAHRA SHAHI, and ZAYNAB MOHKAMI, “ASSESSMENT OF ANTIBACTERIAL ACTIVITIES OF ETHANOLIC EXTRACT OF MYRTUS COMMUNIS (MYRTLE) LEAVES AGAINST MULTIDRUG-RESISTANT ESCHERICHIA COLI,” JOURNAL OF ZABOL UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES (JOURNAL OF ROSTAMINEH), vol. 6, no. 2, pp. 18–25, 2014, [Online]. Available: https://sid.ir/paper/203570/en

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