EVALUATION OF EFFECT OF HONEY AND VITAMIN E ON APOPTOSIS IN TESTES OF RAT EXPOSED TO NOISE STRESS

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RAJABZADEH ASGHAR; SAKI GHASEM; HEMADI MASOUD; KHODADADI ALI; SARKAKI ALIREZA

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Journal: Jentashapir Journal of Cellular and Molecular Biology Year:2013 | Volume:3 | Issue:4 (9) Page(s): 523-532

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Title

EVALUATION OF EFFECT OF HONEY AND VITAMIN E ON APOPTOSIS IN TESTES OF RAT EXPOSED TO NOISE STRESS

Author(s)

Keywords

NOISE STRESSQ2

APOPTOSISQ3

HONEYQ3

VITAMIN EQ3

GERM CELLSQ3

Abstract

Background: Noise pollution causes of APOPTOSIS in germinal cells of testes. This study investigated the effects of HONEY and VITAMIN E administration on the process of APOPTOSIS in cells of the germinal testis of rats exposed to NOISE STRESS.Methods: In this study, 24 male wistar rats randomly grouped as: 1 (honey+NOISE STRESS), 2 (vitamin E+NOISE STRESS) 3 (NOISE STRESS) and group 4 (control) groups. In groups 1, 2 and 3 rats were exposed to NOISE STRESS. After 50 days testesof rats were extracted and digested by using DNaseI, collagenase type IV and trypsin- EDTA then viability and APOPTOSIS of the cells in harvested cell suspension evaluated by using the TUNEL kit.Results: This study showed that the APOPTOSIS was increased and viability decreased in testes of exposed rats to NOISE STRESS. By administrated of HONEY and VITAMIN E we observed that the APOPTOSIS rate significantly decreased (1.89 % and 3.98% in groups received HONEY and vitamin respectively). (p<0.05).Conclusion: This study showed that administration of HONEY and VITAMIN E reduced the effect of NOISE STRESS and APOPTOSIS in germinal cell and recovered spermatogenesis in rats with increase numbers of live cells.

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APA: Copy

RAJABZADEH, ASGHAR, SAKI, GHASEM, HEMADI, MASOUD, KHODADADI, ALI, & SARKAKI, ALIREZA. (2013). EVALUATION OF EFFECT OF HONEY AND VITAMIN E ON APOPTOSIS IN TESTES OF RAT EXPOSED TO NOISE STRESS. JENTASHAPIR JOURNAL OF CELLULAR AND MOLECULAR BIOLOGY (JENTASHAPIR JOURNAL OF HEALTH RESEARCH), 3(4 (9)), 523-532. SID. https://sid.ir/paper/205716/en

Vancouver: Copy

RAJABZADEH ASGHAR, SAKI GHASEM, HEMADI MASOUD, KHODADADI ALI, SARKAKI ALIREZA. EVALUATION OF EFFECT OF HONEY AND VITAMIN E ON APOPTOSIS IN TESTES OF RAT EXPOSED TO NOISE STRESS. JENTASHAPIR JOURNAL OF CELLULAR AND MOLECULAR BIOLOGY (JENTASHAPIR JOURNAL OF HEALTH RESEARCH)[Internet]. 2013;3(4 (9)):523-532. Available from: https://sid.ir/paper/205716/en

IEEE: Copy

ASGHAR RAJABZADEH, GHASEM SAKI, MASOUD HEMADI, ALI KHODADADI, and ALIREZA SARKAKI, “EVALUATION OF EFFECT OF HONEY AND VITAMIN E ON APOPTOSIS IN TESTES OF RAT EXPOSED TO NOISE STRESS,” JENTASHAPIR JOURNAL OF CELLULAR AND MOLECULAR BIOLOGY (JENTASHAPIR JOURNAL OF HEALTH RESEARCH), vol. 3, no. 4 (9), pp. 523–532, 2013, [Online]. Available: https://sid.ir/paper/205716/en

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