THE STUDY OF OXIDATIVE STRESS BIOMARKERS IN CERAMIC WORKERS COMPARED TO A CONTROL GROUP

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KESHVARI SHAD M.; BARKHORDARI A.; RANJBAR A.; MEHRPARVAR A.H.; DEHGHANI A.

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Journal: Tibbi- i- kar Year:2016 | Volume:7 | Issue:4 Page(s): 67-81

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Title

THE STUDY OF OXIDATIVE STRESS BIOMARKERS IN CERAMIC WORKERS COMPARED TO A CONTROL GROUP

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Keywords

CERAMIC WORKERSQ2

OXIDATIVE STRESSQ2

ANTIOXIDANTQ2

LIPID PEROXIDATIONQ2

Abstract

Introduction: The workers who are working in ceramic tile industeries exposed to various kinds of occupational hazardous agents especially metal oxides including silica, lead, aluminum, chromium, cobalt, titanium, zinc, cadmium oxides and other hazardous agents such as sound, infrared radiation, radon gas and heat stress. The present study was carried out to assess the effects of exposure to heavy metals and OXIDATIVE STRESS indices, which may induce related health hazards and occupational diseases.Methods: The present study is an analytical cross-sectional study (historical cohort). Forty male workers in ceramic industry were considered as an experimental group and 39 male employees who were not exposed to any hazardous agents served as a control group. In both groups blood samples were obtained. OXIDATIVE STRESS parameters were evaluated in plasma samples. In order to measured OXIDATIVE STRESS, LIPID PEROXIDATION (LPO), total ANTIOXIDANT capacity (TAC), total thiol groups (TTG) and catalase activity (CAT) were investigated. Statistical analysis was performed using SPSS version 20.Results: The results expressed as mean SD showed induction of OXIDATIVE STRESS in workers as revealed by increased plasma LPO (1.46±0.559 vs 1.15±0.658, nmol/ml P=0.031), CAT (10.273±15.309, 4.817±4.407 vs U/ml P=0.035). TAC (550.88±104.47 vs 807.23±138.52 mmol/ml P=0.000) and TTG (0.388±0.058 vs 0.423±0.095, nmol/ml P=0.028) in comparison to those of controls.Conclusion: These results indicated that long term exposure to heavy metals leads to induction of activity of anti-oxidant enzyme and in general leads to increase in OXIDATIVE STRESS of ceramic industry workers

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APA: Copy

KESHVARI SHAD, M., BARKHORDARI, A., RANJBAR, A., MEHRPARVAR, A.H., & DEHGHANI, A.. (2016). THE STUDY OF OXIDATIVE STRESS BIOMARKERS IN CERAMIC WORKERS COMPARED TO A CONTROL GROUP. OCCUPATIONAL MEDICINE, 7(4), 67-81. SID. https://sid.ir/paper/207072/en

Vancouver: Copy

KESHVARI SHAD M., BARKHORDARI A., RANJBAR A., MEHRPARVAR A.H., DEHGHANI A.. THE STUDY OF OXIDATIVE STRESS BIOMARKERS IN CERAMIC WORKERS COMPARED TO A CONTROL GROUP. OCCUPATIONAL MEDICINE[Internet]. 2016;7(4):67-81. Available from: https://sid.ir/paper/207072/en

IEEE: Copy

M. KESHVARI SHAD, A. BARKHORDARI, A. RANJBAR, A.H. MEHRPARVAR, and A. DEHGHANI, “THE STUDY OF OXIDATIVE STRESS BIOMARKERS IN CERAMIC WORKERS COMPARED TO A CONTROL GROUP,” OCCUPATIONAL MEDICINE, vol. 7, no. 4, pp. 67–81, 2016, [Online]. Available: https://sid.ir/paper/207072/en

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