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Information Journal Paper

Title

ON THE ROLE OF METHANOL IN AMYLOID FORMATION INDUCTION IN APO-YEAST ALCOHOLDEHYDROGENASE

Pages

  35-42

Abstract

AMYLOID formation in non disease proteins has little been studied. In the present study, to reveal the trend of AMYLOID formation in a typical protein, apo I- yeast alcohol dehydrogenase (apo I-YADH) which was obtained by removing of the structural zinc, was subjected to aqueous solution of METHANOL . AMYLOID formation was evaluated by CONGO RED (CR) and THIOFLAVIN T staining method using fluorescence and CD SPECTROSCOPY. The AMYLOID-inducing aptitude of METHANOL showed a concentration dependent manner: 20%< 40% < 60% < 70% < 80%. The established AMYLOID formation monitored by spectroscopic studies, was ascribed to the conformational transition from native to the b-sheet rich structure in the enzyme molecules.

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    APA: Copy

    MIROLIAEI, M., EBRAHIMIAN, B., HOSSEINKHANI, S., & GHASEMI, A.. (2011). ON THE ROLE OF METHANOL IN AMYLOID FORMATION INDUCTION IN APO-YEAST ALCOHOLDEHYDROGENASE. IRANIAN JOURNAL OF BIOLOGY, 24(1), 35-42. SID. https://sid.ir/paper/21467/en

    Vancouver: Copy

    MIROLIAEI M., EBRAHIMIAN B., HOSSEINKHANI S., GHASEMI A.. ON THE ROLE OF METHANOL IN AMYLOID FORMATION INDUCTION IN APO-YEAST ALCOHOLDEHYDROGENASE. IRANIAN JOURNAL OF BIOLOGY[Internet]. 2011;24(1):35-42. Available from: https://sid.ir/paper/21467/en

    IEEE: Copy

    M. MIROLIAEI, B. EBRAHIMIAN, S. HOSSEINKHANI, and A. GHASEMI, “ON THE ROLE OF METHANOL IN AMYLOID FORMATION INDUCTION IN APO-YEAST ALCOHOLDEHYDROGENASE,” IRANIAN JOURNAL OF BIOLOGY, vol. 24, no. 1, pp. 35–42, 2011, [Online]. Available: https://sid.ir/paper/21467/en

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