SURVEY OF EFFECTIVENESS OF INTRATHECAL ADMINISTRATION OF COMBINATION OF SUFENTANIL AND MORPHINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPARATOMY

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SEDIGHINEJAD ABBAS; NADERI NABI BAHRAM; HAGHIGHI MOHAMMAD; MOHAMMADZADEH JORYABI ALI; IMANTALAB VALI; MIRMANSOURI ALI; KHOSHRANG HOSEIN

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Journal: Journal of Anesthesiology and Pain Year:2011 | Volume:1 | Issue:3 Page(s): 32-40

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Title

SURVEY OF EFFECTIVENESS OF INTRATHECAL ADMINISTRATION OF COMBINATION OF SUFENTANIL AND MORPHINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPARATOMY

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Keywords

SUFENTANILQ2

MORPHINEQ3

INTRATHECAL OPIOIDS INJECTIONQ2

POSTOPERATIVE ANALGESIAQ3

LAPARATOMYQ3

Abstract

Background: There are many methods to provide pain relief after operation, that includes: IV or IM opioids injections, patient controledl analgesia, uses NSAIDs useing (IM, IV or rectal).All of these methods have advantages and disadvantages. Another techniques for post operative analgesia is epidural catheter insertion and administration of opioids or local anesthetic continously. The goal of this study is to compare intrathecal administration of combination of SUFENTANIL and MORPHINE for postoperative pain relief after LAPARATOMY.Materials and Methods: 40 ASA I-III patients who were candidates for laparatomic surgeries enrolled in two groups in this clinical trial study after written inform consent (randomly assigned).One group (N=20) before general anesthesia received a spinal injection of SUFENTANIL (5m) and MORPHINE (0.3 mg) (S-M groups) and another group (control group) didn't receive intrathecal opioids.Post-operative pain was rated on a visual analogue scale (VAS) at rest in 6 and 12 hours after operation and also total dose of injected MORPHINE for 24 hours after operation calculated. The data were analyzed by SPSS16, T-test, Chi-Square and paired T-test.Results: Intrathecal injection of SUFENTANIL and MORPHINE caused VAS scores at rest were significantly higher in the control group in 6 and 12 hours after operation and total dose of MORPHINE consumption was significantly lower in the SM group.Conclusion: Combination of intrathecal SUFENTANIL and MORPHINE produce good analgesic effect after laparatomic surgery at 12 hours after operation.

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APA: Copy

SEDIGHINEJAD, ABBAS, NADERI NABI, BAHRAM, HAGHIGHI, MOHAMMAD, MOHAMMADZADEH JORYABI, ALI, IMANTALAB, VALI, MIRMANSOURI, ALI, & KHOSHRANG, HOSEIN. (2011). SURVEY OF EFFECTIVENESS OF INTRATHECAL ADMINISTRATION OF COMBINATION OF SUFENTANIL AND MORPHINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPARATOMY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 1(3), 32-40. SID. https://sid.ir/paper/216242/en

Vancouver: Copy

SEDIGHINEJAD ABBAS, NADERI NABI BAHRAM, HAGHIGHI MOHAMMAD, MOHAMMADZADEH JORYABI ALI, IMANTALAB VALI, MIRMANSOURI ALI, KHOSHRANG HOSEIN. SURVEY OF EFFECTIVENESS OF INTRATHECAL ADMINISTRATION OF COMBINATION OF SUFENTANIL AND MORPHINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPARATOMY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2011;1(3):32-40. Available from: https://sid.ir/paper/216242/en

IEEE: Copy

ABBAS SEDIGHINEJAD, BAHRAM NADERI NABI, MOHAMMAD HAGHIGHI, ALI MOHAMMADZADEH JORYABI, VALI IMANTALAB, ALI MIRMANSOURI, and HOSEIN KHOSHRANG, “SURVEY OF EFFECTIVENESS OF INTRATHECAL ADMINISTRATION OF COMBINATION OF SUFENTANIL AND MORPHINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPARATOMY,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 1, no. 3, pp. 32–40, 2011, [Online]. Available: https://sid.ir/paper/216242/en

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