COMPARISON BETWEEN INTRAVENOUS ACETAMINOPHEN AND REMIFENTANIL ON THE AIRWAY RESPONSE TO TRACHEAL TUBE IN ENDOSCOPIC SINUS SURGERY, DURING AND AT THE END OF ANESTHESIA

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HASSANI VALIOLLAH; FARHADI MOHAMAD; ZAMAN BEHROUZ; AALI NASIME; SAFAEIAN REZA; SAYARIFARD AZADEH

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Journal: Journal of Anesthesiology and Pain Year:2014 | Volume:4 | Issue:3 Page(s): 54-61

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Title

COMPARISON BETWEEN INTRAVENOUS ACETAMINOPHEN AND REMIFENTANIL ON THE AIRWAY RESPONSE TO TRACHEAL TUBE IN ENDOSCOPIC SINUS SURGERY, DURING AND AT THE END OF ANESTHESIA

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Keywords

INTRAVENOUS ACETAMINOPHENQ2

REMIFENTANILQ3

ENDOSCOPIC SINUS SURGERYQ2

Abstract

Aims and Background: Airway hyperactivity is one of the most important complications of tracheal extubation. This study was designed to compare the efficacy of INTRAVENOUS ACETAMINOPHEN as an alternative to REMIFENTANIL on airway response to tracheal tubes during and at the end of anesthesia in functional ENDOSCOPIC SINUS SURGERY. Methods and materials: This study was conducted as a double blind clinical trial on 70 patients 20 to 60 years old, candidate for ENDOSCOPIC SINUS SURGERY, in Rasoul-Akram hospital. They were randomly allocated into two groups: the Paracetamol (n=35) and the REMIFENTANIL (n=35) groups. REMIFENTANIL infusion with a dose of 0.1mg/ kg/min was administered for both groups during anesthesia. Since the beginning of inserting the nose tampon until extubation, REMIFENTANIL infusion (0.1 mg/kg/min) was continued in group I, and in group II in the last 20 minutes of surgery, REMIFENTANIL infusion was discontinued and intravenous injection of acetaminophen was begun. Incidece of Cough, Arterial blood pressure, and heart rate were recorded.Findings: There was no significant difference in the incidence rate of cough during extubation between the two groups (P=0.7). Mean arterial pressure (MAP) variation, was significantly lower in the REMIFENTANIL group (P<0.001). Variations in heart rate were similar in both groups (P=0.74). Conclusions: Using INTRAVENOUS ACETAMINOPHEN has the same effect as REMIFENTANIL in controling airway reflexes after ENDOSCOPIC SINUS SURGERY as well as reducing symptoms such as restlessness and changes in heart rate.

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APA: Copy

HASSANI, VALIOLLAH, FARHADI, MOHAMAD, ZAMAN, BEHROUZ, AALI, NASIME, SAFAEIAN, REZA, & SAYARIFARD, AZADEH. (2014). COMPARISON BETWEEN INTRAVENOUS ACETAMINOPHEN AND REMIFENTANIL ON THE AIRWAY RESPONSE TO TRACHEAL TUBE IN ENDOSCOPIC SINUS SURGERY, DURING AND AT THE END OF ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 4(3), 54-61. SID. https://sid.ir/paper/216273/en

Vancouver: Copy

HASSANI VALIOLLAH, FARHADI MOHAMAD, ZAMAN BEHROUZ, AALI NASIME, SAFAEIAN REZA, SAYARIFARD AZADEH. COMPARISON BETWEEN INTRAVENOUS ACETAMINOPHEN AND REMIFENTANIL ON THE AIRWAY RESPONSE TO TRACHEAL TUBE IN ENDOSCOPIC SINUS SURGERY, DURING AND AT THE END OF ANESTHESIA. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2014;4(3):54-61. Available from: https://sid.ir/paper/216273/en

IEEE: Copy

VALIOLLAH HASSANI, MOHAMAD FARHADI, BEHROUZ ZAMAN, NASIME AALI, REZA SAFAEIAN, and AZADEH SAYARIFARD, “COMPARISON BETWEEN INTRAVENOUS ACETAMINOPHEN AND REMIFENTANIL ON THE AIRWAY RESPONSE TO TRACHEAL TUBE IN ENDOSCOPIC SINUS SURGERY, DURING AND AT THE END OF ANESTHESIA,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 4, no. 3, pp. 54–61, 2014, [Online]. Available: https://sid.ir/paper/216273/en

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