EFFECT OF SINGLE DOSE PREMEDICATION WITH PREGABALINE ON PAIN AFTER MINOR SURGERY

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IMANI FARNAD; NEZAFATI MAHMOUD; HEIDARIAN MAJID; MOLLA SOLTANI MOHAMMAD; NIKNAM KEIVAN

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Journal: Journal of Anesthesiology and Pain Year:2012 | Volume:2 | Issue:8 Page(s): 180-185

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Title

EFFECT OF SINGLE DOSE PREMEDICATION WITH PREGABALINE ON PAIN AFTER MINOR SURGERY

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Keywords

PREGABALINQ2

MINOR GENERAL SURGERYQ3

PAIN SCOREQ2

PREMEDICATIONQ2

Abstract

Aim and Background: Optimal postoperative pain management is necessary after MINOR GENERAL SURGERY. Although PREGABALIN had been showed efficacy against neuropathic pain, very limited evidence support its postoperative analgesic efficacy. The aim of this study was to evaluate the analgesic efficacy of PREMEDICATION with single oral dose of PREGABALIN for MINOR GENERAL SURGERY.Methods and Materials: Sixty patients candidate for MINOR GENERAL SURGERY under general anesthesia were randomly allocated into the two groups, In intervention group PREGABALIN 150 mg, and in control group placebo was administered one hour before surgery. Anesthesia method was similar in both groups. If PAIN SCORE (Visual Analogue Scale, VAS) was more than three, pethidine 25mg intravenous was administrated. VAS, opioid consumption, and side effects were recorded for 24 hours after surgery.Findings: Demographic data was not significantly different between two groups. VAS and opioid consumption during the 24 hours postoperative period in PREGABALIN group was significantly less than the placebo group without any more side effects (p<0.01).Conclusions: Preoperative administration of single oral dose of PREGABALIN 150 mg reduced post operative pain and opioid consumption for 24 hours following MINOR GENERAL SURGERY.

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APA: Copy

IMANI, FARNAD, NEZAFATI, MAHMOUD, HEIDARIAN, MAJID, MOLLA SOLTANI, MOHAMMAD, & NIKNAM, KEIVAN. (2012). EFFECT OF SINGLE DOSE PREMEDICATION WITH PREGABALINE ON PAIN AFTER MINOR SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 2(8), 180-185. SID. https://sid.ir/paper/216290/en

Vancouver: Copy

IMANI FARNAD, NEZAFATI MAHMOUD, HEIDARIAN MAJID, MOLLA SOLTANI MOHAMMAD, NIKNAM KEIVAN. EFFECT OF SINGLE DOSE PREMEDICATION WITH PREGABALINE ON PAIN AFTER MINOR SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2012;2(8):180-185. Available from: https://sid.ir/paper/216290/en

IEEE: Copy

FARNAD IMANI, MAHMOUD NEZAFATI, MAJID HEIDARIAN, MOHAMMAD MOLLA SOLTANI, and KEIVAN NIKNAM, “EFFECT OF SINGLE DOSE PREMEDICATION WITH PREGABALINE ON PAIN AFTER MINOR SURGERY,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 2, no. 8, pp. 180–185, 2012, [Online]. Available: https://sid.ir/paper/216290/en

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