AN EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE SULFATE IN PATIENTS RECEIVING INTRAVENOUS PCA AFTER ORTHOPEDIC SURGERY

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IMANI FARNAD; AKHAVAN AKBARI GHODRAT; MOHAMMADIAN ERDI ALI; RAHIMZADEH PUOPAK

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Journal: Journal of Anesthesiology and Pain Year:2011 | Volume:1 | Issue:4 Page(s): 72-78

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Title

AN EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE SULFATE IN PATIENTS RECEIVING INTRAVENOUS PCA AFTER ORTHOPEDIC SURGERY

Author(s)

IMANI FARNAD | AKHAVAN AKBARI GHODRAT | MOHAMMADIAN ERDI ALI | RAHIMZADEH PUOPAK | Issue Writer Certificate

Keywords

PREGABALINQ2

MORPHINEQ3

ORTHOPEDIC SURGERYQ2

PAIN SCOREQ2

Abstract

Background and aims: Although PREGABALIN shows efficacy against neuropathic pain, very limited evidence support postoperative analgesic efficacy. Our study objective to investigate analgesic efficacy of oral PREGABALIN in ORTHOPEDIC SURGERY postoperative pain and opioid consumption.Materials and methods: A randomized, double-blind, placebo-controlled was performed in ORTHOPEDIC SURGERY. Patients received in first group (30 patients) PCA MORPHINE (20 mg/100ml) and in second group (30 patients) PCA MORPHINE (10 mg/100ml) +oral PREGABALIN 300 mg daily for 48h after surgery. PAIN SCORE (VAS) and opioid consumption assessed in 48 hr after surgery.Results: There was not significant difference between groups for demographic data. PAIN SCORE and opioid consumption in PREGABALINe group was significantly lower than MORPHINE group without any significant complications.Conclusions: preoperative oral dose of 300 mg PREGABALIN dailyfor 48h after surgery reduces post operative acute pain in ORTHOPEDIC SURGERY.

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APA: Copy

IMANI, FARNAD, AKHAVAN AKBARI, GHODRAT, MOHAMMADIAN ERDI, ALI, & RAHIMZADEH, PUOPAK. (2011). AN EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE SULFATE IN PATIENTS RECEIVING INTRAVENOUS PCA AFTER ORTHOPEDIC SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 1(4), 72-78. SID. https://sid.ir/paper/216319/en

Vancouver: Copy

IMANI FARNAD, AKHAVAN AKBARI GHODRAT, MOHAMMADIAN ERDI ALI, RAHIMZADEH PUOPAK. AN EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE SULFATE IN PATIENTS RECEIVING INTRAVENOUS PCA AFTER ORTHOPEDIC SURGERY. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2011;1(4):72-78. Available from: https://sid.ir/paper/216319/en

IEEE: Copy

FARNAD IMANI, GHODRAT AKHAVAN AKBARI, ALI MOHAMMADIAN ERDI, and PUOPAK RAHIMZADEH, “AN EVALUATION OF THE EFFECTS OF ADDING ORAL PREGABALINE TO MORPHINE SULFATE IN PATIENTS RECEIVING INTRAVENOUS PCA AFTER ORTHOPEDIC SURGERY,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 1, no. 4, pp. 72–78, 2011, [Online]. Available: https://sid.ir/paper/216319/en

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