ANALGESIC EFFICACY OF PREOPERATIVE ORAL PREGABALIN IN LOWER LIMB FRACTURES

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AKHAVAN AKBARI GHODRAT; ENTEZARI ASL MASOUD; ISAZADEFAR KHATERE; MIRZARAHIMI TIBA

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Journal Paper

Paper Information

Journal: Journal of Anesthesiology and Pain Year:2013 | Volume:3 | Issue:3 Page(s): 135-141

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Information Journal Paper

Title

ANALGESIC EFFICACY OF PREOPERATIVE ORAL PREGABALIN IN LOWER LIMB FRACTURES

Author(s)

AKHAVAN AKBARI GHODRAT | ENTEZARI ASL MASOUD | ISAZADEFAR KHATERE | MIRZARAHIMI TIBA | Issue Writer Certificate

Keywords

PREGABALINQ2

LOWER LIMB FRACTUREQ2

PAINQ2

VISUAL ANALOG PAIN SCORESQ2

Abstract

Aim and Background: Inadequate postoperative PAIN control results in many complications. A feasible and effective modality is warranted. In this study we evaluated the analgesic efficacy of preoperative PREGABALIN in lower limb orthopedic surgery.Methods and Materials: This double blind clinical trial study was carried out on 60 patients candidate for lower limb orthopedic surgery. Patients were randomly allocated to receive either 150 mg PREGABALIN capsule or placebo two hours before surgery. Severity of PAIN, nausea and Ramsay sedation scores were evaluated 2, 6, 12 and 24 hours, postoperatively. Findings: Visual analog PAIN scores, administered dose of pethidine and nausea scores in the PREGABALIN group were significantly lower than placebo group. Patients in the PREGABALIN group were more sedated in the 2nd and 6th hour postoperatively.Conclusions: Preoperative administration of PREGABALIN can effectively reduce PAIN and required dose of opioids after lower limb orthopedic surgery.

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APA: Copy

AKHAVAN AKBARI, GHODRAT, ENTEZARI ASL, MASOUD, ISAZADEFAR, KHATERE, & MIRZARAHIMI, TIBA. (2013). ANALGESIC EFFICACY OF PREOPERATIVE ORAL PREGABALIN IN LOWER LIMB FRACTURES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), 3(3), 135-141. SID. https://sid.ir/paper/216347/en

Vancouver: Copy

AKHAVAN AKBARI GHODRAT, ENTEZARI ASL MASOUD, ISAZADEFAR KHATERE, MIRZARAHIMI TIBA. ANALGESIC EFFICACY OF PREOPERATIVE ORAL PREGABALIN IN LOWER LIMB FRACTURES. JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN)[Internet]. 2013;3(3):135-141. Available from: https://sid.ir/paper/216347/en

IEEE: Copy

GHODRAT AKHAVAN AKBARI, MASOUD ENTEZARI ASL, KHATERE ISAZADEFAR, and TIBA MIRZARAHIMI, “ANALGESIC EFFICACY OF PREOPERATIVE ORAL PREGABALIN IN LOWER LIMB FRACTURES,” JOURNAL OF ANESTHESIOLOGY AND PAIN (PERSIAN), vol. 3, no. 3, pp. 135–141, 2013, [Online]. Available: https://sid.ir/paper/216347/en

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