The Effect of High Intensity Interval Training on Serum Levels and Gene Expression of Tfam and PGC1α in Hippocampus of Male Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Sharafi Dehrahm Firuz; SOORI RAHMAN; ABBASIAN SADEGH; Rastegar Moghaddam Mansouri Mahsa

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Sport Physiology and Management Investigations Year:2019 | Volume:11 | Issue:2 Page(s): 75-85

Download Full-Text

Persian Verion

View:

438

Download:

Cites:

Information Journal Paper

Title

The Effect of High Intensity Interval Training on Serum Levels and Gene Expression of Tfam and PGC1α in Hippocampus of Male Rats

Author(s)

Sharafi Dehrahm Firuz | SOORI RAHMAN | ABBASIAN SADEGH | Rastegar Moghaddam Mansouri Mahsa | Issue Writer Certificate

Keywords

TrainingQ1

Mitochondria Transcription Factors HippocampusQ1

Abstract

Mitochondrial transcription factor A (Tfam) has a key role in keeping copy numbers and transcription activity of mtDNA. The aim of the present study was to determine the effect of high intensity interval Training (HIIT) on mitochondrial biogenesis factors in hippocampus of male rats. In the present study, 20 Wistar rats were assigned to HIIT and control groups. Training protocol was performed 60 min. each session for four sessions a week. Training group carried out 15 × 4 min. bouts of Training with 85-90% of VO2max with 3 min. recovery with 70% of VO2max (between HIIT bouts). Then, blood samples and tissue samples of hippocampus were collected. PGC1α and Tfam and their gene translations were evaluated by commercial kits and Real-Time PCR method respectively. Results illustrated that VO2max and serum levels of PGC1α and Tfam significantly increased (P<0. 05). Also, the amounts of PGC1α and Tfam gene expressions in hippocampus significantly increased in Training group compared with the control group (P<0. 05). It seems that the present three-week HIIT protocol on the treadmill can significantly increase both hippocampus and serum levels of PGC1α and Tfam in male rats. Likewise, there is a likelihood that significant increase of Tfam is due to significant and increasing changes of PGC1α .

Cites

No record.

References

No record.

Cite

APA: Copy

Sharafi Dehrahm, Firuz, SOORI, RAHMAN, ABBASIAN, SADEGH, & Rastegar Moghaddam Mansouri, Mahsa. (2019). The Effect of High Intensity Interval Training on Serum Levels and Gene Expression of Tfam and PGC1α in Hippocampus of Male Rats. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, 11(2 ), 75-85. SID. https://sid.ir/paper/222334/en

Vancouver: Copy

Sharafi Dehrahm Firuz, SOORI RAHMAN, ABBASIAN SADEGH, Rastegar Moghaddam Mansouri Mahsa. The Effect of High Intensity Interval Training on Serum Levels and Gene Expression of Tfam and PGC1α in Hippocampus of Male Rats. SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS[Internet]. 2019;11(2 ):75-85. Available from: https://sid.ir/paper/222334/en

IEEE: Copy

Firuz Sharafi Dehrahm, RAHMAN SOORI, SADEGH ABBASIAN, and Mahsa Rastegar Moghaddam Mansouri, “The Effect of High Intensity Interval Training on Serum Levels and Gene Expression of Tfam and PGC1α in Hippocampus of Male Rats,” SPORT PHYSIOLOGY & MANAGEMENT INVESTIGATIONS, vol. 11, no. 2 , pp. 75–85, 2019, [Online]. Available: https://sid.ir/paper/222334/en

Related Journal Papers