THE EFFECT OF IMM UN OSUPPRESIVE CHEMOTHERAPY ON THE MICROJLORA OF ORAL CAVITY IN LEUKEMIC CHILDREN

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FATHIEH A.; SAFAEI M.

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Journal: Journal of Dental School Year:2002 | Volume:20 | Issue:3 Page(s): 336-343

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Title

THE EFFECT OF IMM UN OSUPPRESIVE CHEMOTHERAPY ON THE MICROJLORA OF ORAL CAVITY IN LEUKEMIC CHILDREN

Author(s)

FATHIEH A. | SAFAEI M. | Issue Writer Certificate

Keywords

CHEMOTHERAPYQ4

ORAL MICROFLORAQ4

LEUKAEMIAQ4

Abstract

Background: There is not enough research evidence to support specific treatment plan for leukemia patients before and after CHEMOTHERAPY. One of the complications in leukemic patients is the increased incidence of infection due to reduction of defense mechanism and consumption of immunosuppressive drugs. In addition, the normal flora of these patients changes during CHEMOTHERAPY. Aim: This research was designed to study the changes of oral flora before and after CHEMOTHERAPY in leukemic patients. Method & Material: This study was performed on 22 Leukemic patients, of whom 2 died later, leaving 14male and 6 female with the mean age of 8 (5-12 Years). Out of these 20 patients, 12 were suffering from acute lymphocytic leukemia and 8 from acute myelocytic leukemia. The first sample was taken before hospitalization while the second one was one month after the beginning of CHEMOTHERAPY. Microbial culture was provided followed by colony count for each sample. Results: Results showed a reduction in the number of colonies of streptococcus, Neisseria, Diphtheroids and also an increase in that of staphylococcus, Pseudomonas, Escherichia coli, Klebsiella, Enterobacter and Candida. Conclusion: Variability of micro organisms including gram negatives, introduces the need for provisional dental treatment plans for leukemia patients.

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APA: Copy

FATHIEH, A., & SAFAEI, M.. (2002). THE EFFECT OF IMM UN OSUPPRESIVE CHEMOTHERAPY ON THE MICROJLORA OF ORAL CAVITY IN LEUKEMIC CHILDREN. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 20(3), 336-343. SID. https://sid.ir/paper/22271/en

Vancouver: Copy

FATHIEH A., SAFAEI M.. THE EFFECT OF IMM UN OSUPPRESIVE CHEMOTHERAPY ON THE MICROJLORA OF ORAL CAVITY IN LEUKEMIC CHILDREN. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2002;20(3):336-343. Available from: https://sid.ir/paper/22271/en

IEEE: Copy

A. FATHIEH, and M. SAFAEI, “THE EFFECT OF IMM UN OSUPPRESIVE CHEMOTHERAPY ON THE MICROJLORA OF ORAL CAVITY IN LEUKEMIC CHILDREN,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 20, no. 3, pp. 336–343, 2002, [Online]. Available: https://sid.ir/paper/22271/en

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