EVALUATION OF CHARACTERISTICS OF CHILDREN WITH LEUKEMIA IN KASHAN AREA FROM 1994-1999 AND

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MOMTAZMANESH N.; VAZIRI S.; TAGHADOSI M.

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Journal: Feyz Medical Sciences Journal Year:2000 | Volume:4 | Issue:14 Page(s): 103-109

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Title

EVALUATION OF CHARACTERISTICS OF CHILDREN WITH LEUKEMIA IN KASHAN AREA FROM 1994-1999 AND

Author(s)

MOMTAZMANESH N. | VAZIRI S. | TAGHADOSI M. | Issue Writer Certificate

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Abstract

History and Objectives: Because leukemia is the most common disease and one of the cruable malignancies in children, the present study was performed for the determination of characteristics of children with leukemia in Kashan area. Materials and Methods: The present study was carried out on exsiting data of patients undergone diagnostic procedures and treatment in the ward of pediatric disease. Demographic, clinical, laboratory, cytogenetic and immunophenotype characteristics of patients were evaluated. Results: The study showed that frequency of leukemia in children before 1years old 5.5%. ALL, AML frequency were 89% and 11% respectively. The most common clinical symptoms were paleness (60.5%) hemorrhage (50%) and fever (44%). 17% of cases had WEC count more than 5000/mm3 and 27.5% of cases had platelet count less than 50,000. Relapse occurred in 22% of cases with the bone marrow the most common place (11%). Frequency of leukemia was 55.5% in boys and 44.5% in girls. 50% of patients had anemia. From cytogenetic point of view 44.5% were diploid and 5.5% aneuploid and evaluation was not performed for the rest. From immunophenotype point of view cases were divided to ALL with B cell origin (50%), ALL with T cell origin (11%), ALL with unknown origin (5.5%), AML (11%) and this evaluation wasn't performed for the 4 cases. Conclusions: Due to nonspecific clinical signs and symptoms of leukemia among children, for early diagnosis and treatment, more precise examination by physicians is emphasized. Also more extensive studies on the prognosis of patients is suggested.

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APA: Copy

MOMTAZMANESH, N., VAZIRI, S., & TAGHADOSI, M.. (2000). EVALUATION OF CHARACTERISTICS OF CHILDREN WITH LEUKEMIA IN KASHAN AREA FROM 1994-1999 AND. FEYZ, 4(14), 103-109. SID. https://sid.ir/paper/40475/en

Vancouver: Copy

MOMTAZMANESH N., VAZIRI S., TAGHADOSI M.. EVALUATION OF CHARACTERISTICS OF CHILDREN WITH LEUKEMIA IN KASHAN AREA FROM 1994-1999 AND. FEYZ[Internet]. 2000;4(14):103-109. Available from: https://sid.ir/paper/40475/en

IEEE: Copy

N. MOMTAZMANESH, S. VAZIRI, and M. TAGHADOSI, “EVALUATION OF CHARACTERISTICS OF CHILDREN WITH LEUKEMIA IN KASHAN AREA FROM 1994-1999 AND,” FEYZ, vol. 4, no. 14, pp. 103–109, 2000, [Online]. Available: https://sid.ir/paper/40475/en

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