COLORIMETRIC DETECTION OF TNT USING APTASENSOR BASED ON GOLD-NANOPARTICLE

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BARKHEH HOSSEIN; ZEINODDINI MEHDI; RANJBAR BIJAN

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Paper Information

Journal: Journal of Police Medicine Year:2016 | Volume:5 | Issue:3 Page(s): 177-186

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Information Journal Paper

Title

COLORIMETRIC DETECTION OF TNT USING APTASENSOR BASED ON GOLD-NANOPARTICLE

Author(s)

BARKHEH HOSSEIN | ZEINODDINI MEHDI | RANJBAR BIJAN | Issue Writer Certificate

Keywords

APTASENSORQ3

TNTQ3

GOLD NANOPARTICLESQ3

COLORIMETRIC DETECTIONQ3

Abstract

Background: Current study is aimed at designing and producing gold-nanoparticle based APTASENSOR for COLORIMETRIC DETECTION of tri-nitro toluene (TNT).Materials and Methods: Gold-nanoparticles have a wide range of application in designing biosensors for their special and highly sensitive plasmonic characteristics. In the present study, TNT molecule has been detected by designing and producing gold nanoparticle based APTASENSOR. After synthesizing GOLD NANOPARTICLES and functionalizing them by ssDNA aptamer having 52 nucleotides, APTASENSOR performance for detecting target molecule was evaluated. Techniques such as dynamic light scattering (DLS), transmission electron micro-scope and UV-Vis spectrophotometer were used to characterize the size and shape of nanoparticles, functionalizing them by aptamer, and also their sensitivity to detect target.Results: UV-Vis spectrophotometer, DLS, and TEM microscopy tests indicated that GOLD NANOPARTICLES were synthesized with excel-lent quality and average size of 40 nm. TNT molecule was colorimetric detected with sensitivity of 15 nanomolar using gold nanoparticle based APTASENSOR.Conclusion: According to the results it can argue that the strategy promises a novel method in detection due to wide range of such APTASENSORs detection. .

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References

GOLD NANOPARTICLES AS SENSITIVE OPTICAL PROBES

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APA: Copy

BARKHEH, HOSSEIN, ZEINODDINI, MEHDI, & RANJBAR, BIJAN. (2016). COLORIMETRIC DETECTION OF TNT USING APTASENSOR BASED ON GOLD-NANOPARTICLE. POLICE MEDICINE, 5(3), 177-186. SID. https://sid.ir/paper/227933/en

Vancouver: Copy

BARKHEH HOSSEIN, ZEINODDINI MEHDI, RANJBAR BIJAN. COLORIMETRIC DETECTION OF TNT USING APTASENSOR BASED ON GOLD-NANOPARTICLE. POLICE MEDICINE[Internet]. 2016;5(3):177-186. Available from: https://sid.ir/paper/227933/en

IEEE: Copy

HOSSEIN BARKHEH, MEHDI ZEINODDINI, and BIJAN RANJBAR, “COLORIMETRIC DETECTION OF TNT USING APTASENSOR BASED ON GOLD-NANOPARTICLE,” POLICE MEDICINE, vol. 5, no. 3, pp. 177–186, 2016, [Online]. Available: https://sid.ir/paper/227933/en

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