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Title

THE RELATIONSHIP BETWEEN PRO-INFLAMMATORY FACTORS AND VASCULAR FUNCTION AFTER A PERIOD OF CIRCUIT COMBINED TRAINING (RESISTANCE AND ENDURANCE) IN ELDERLY WOMEN

Pages

  45-53

Abstract

 Background: Aging is associated with low-grade INFLAMMATION and vascular endothelial dysfunction. The benefits of regular exercise for well-being in ELDERLY are well established. However, fewer studies have been done about the impact of circuit combined training (CCT) (resistance and endurance) on pro-inflammatory factors associated with vascular function in ELDERLY women.Materials and methods: Subjects were 24 healthy women (age: 73.95±5.06 years, height: 154.26±6.47 cm, weight: 66.13±9.87 kg, BMI: 27.76±3.27 kg/m2) living in nursing homes. They were divided into two groups, including experimental (n=12) and control (n=12) groups. Experimental group participated 12 weeks of CCT protocol. Anthropometric indices, flow mediated dilation (FMD), IL-6, IL-1b, and TNF-a were measured before and after the training program.Results: The analysis of covariance showed a significant reduction in IL-6 (p=0.001), IL-1b (p=0.001), and TNF-a (p=0.000), and a significant increase in FMD (p=0.001), in the experimental group compared to the control after the training program. In Pearson's correlation coefficient test, a non-significant indirect relationship was observed between FMD and three factors of IL-6 (r= -0.26, p=0.41), IL-1b (r= -0.37, p=0.23), and TNF-a (r= -0.17, p=0.59).Conclusion: In summary, the results indicated that 12 weeks of CCT is effective on pro-inflammatory CYTOKINES associated with vascular function in old women aged 70 - 80 years. Also, pro-inflammatory CYTOKINES showed an indirect and weak relationship with vascular function in old women. So, we can probably say that vascular function can improve clinically with a reduction in pro-inflammatory CYTOKINES clinically after CCT protocol in old women. However, further researches are required.

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    APA: Copy

    DEHGHAN, SH., MATINHOMAEE, H., PEERI, M., & FARAMARZI, M.. (2017). THE RELATIONSHIP BETWEEN PRO-INFLAMMATORY FACTORS AND VASCULAR FUNCTION AFTER A PERIOD OF CIRCUIT COMBINED TRAINING (RESISTANCE AND ENDURANCE) IN ELDERLY WOMEN. EBNESINA, 19(1 (58)), 45-53. SID. https://sid.ir/paper/228567/en

    Vancouver: Copy

    DEHGHAN SH., MATINHOMAEE H., PEERI M., FARAMARZI M.. THE RELATIONSHIP BETWEEN PRO-INFLAMMATORY FACTORS AND VASCULAR FUNCTION AFTER A PERIOD OF CIRCUIT COMBINED TRAINING (RESISTANCE AND ENDURANCE) IN ELDERLY WOMEN. EBNESINA[Internet]. 2017;19(1 (58)):45-53. Available from: https://sid.ir/paper/228567/en

    IEEE: Copy

    SH. DEHGHAN, H. MATINHOMAEE, M. PEERI, and M. FARAMARZI, “THE RELATIONSHIP BETWEEN PRO-INFLAMMATORY FACTORS AND VASCULAR FUNCTION AFTER A PERIOD OF CIRCUIT COMBINED TRAINING (RESISTANCE AND ENDURANCE) IN ELDERLY WOMEN,” EBNESINA, vol. 19, no. 1 (58), pp. 45–53, 2017, [Online]. Available: https://sid.ir/paper/228567/en

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