Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’ s Striae: A Contralateral Eye Study

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SEDAGHAT M.R.; OSTADI MOGHADAM H.; ASKARIZADEH F.; NAROOIE NOORI F.; RAJABI S.; Rakhshandadi T.; HASHEMIAN H.

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Journal: Journal of Paramedical Science and Rehabilitation Year:2018 | Volume:7 | Issue:3 Page(s): 7-16

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Title

Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’ s Striae: A Contralateral Eye Study

Author(s)

Keywords

Corneal topographyQ2

KeratoconusQ1

Vogt`s striaeQ1

Abstract

Purpose: The aim of this study was to evaluate and compare topographic characteristics in bilateral Keratoconus (KCN) patients with unilateral Vogt’ s striae. Methods: In this prospective cross-sectional contralateral eye study, the KCN patients that were enrolled in this study had a reliable diagnosis of bilateral clinical KCN with unilateral Vogt`s striae based on slit-lamp signs, as well as corneal topographic/tomographic maps. All the cases underwent a comprehensive ophthalmic examination, including uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), cycloplegic refraction (calculated by vectorial analysis), and placido disc-based Tomey topographer (TMS-4; Tomey, Germany). In this study, clinical and topographic characteristics of all cases were evaluated and compared between the contralateral KCN eyes with Vogt`s striae and those without Vogt`s striae. Paired sample t-test was used to compare the parameters with a normal distribution and the Wilcoxon signed rank test was used to compare the non-parametric parameters. P-value <0. 05 is statistically significant. Results: Fifty patients aged 20 to 38 years (27. 43± 5. 46) were recruited in this study. Our results showed that there were significant differences in sphere, cylinder, spherical equivalent, UDVA, CDVA and J0 (all p<0. 001) except for J45 (p=0. 58) between the contralateral eyes of KCN patients. In KCN eyes with Vogt’ s striae, flat (46. 48± 3. 33 vs 44. 44± 2. 22, p<0. 001), steep (52. 48± 4. 39 vs 47. 02± 3. 26, p<0. 001), minimum (46. 36± 3. 37 vs 44. 35± 2. 17, p<0. 001) and average keratometry (49. 27± 3. 96 vs 45. 74± 2. 60, P<0. 001) as well as Surface Regularity Index (1. 39± 1. 12 vs 0. 52± 0. 41, p<0. 001), Surface Asymmetry Index (2. 32± 1. 25 vs 1. 42± 1. 04, P<0. 001), Keratoconus Index (75. 07± 28. 83 vs 48. 01± 33. 52, p<0. 001) and Keratoconus Severity Index (65. 88± 22. 25 vs 38. 61± 29. 40, p<0. 001)were higher than the contralateral eye without Vogt’ s striae. Conclusion: Corneal topographic parameters showed a significant difference between the contralateral KCN eyes with and without Vogt’ s striae. These results should be noticed in clinical evaluations and treatments of KCN patients.

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References

Stromal striae: a new insight into corneal physiology and mechanics

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APA: Copy

SEDAGHAT, M.R., OSTADI MOGHADAM, H., ASKARIZADEH, F., NAROOIE NOORI, F., RAJABI, S., Rakhshandadi, T., & HASHEMIAN, H.. (2018). Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’ s Striae: A Contralateral Eye Study. JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR), 7(3 ), 7-16. SID. https://sid.ir/paper/245425/en

Vancouver: Copy

SEDAGHAT M.R., OSTADI MOGHADAM H., ASKARIZADEH F., NAROOIE NOORI F., RAJABI S., Rakhshandadi T., HASHEMIAN H.. Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’ s Striae: A Contralateral Eye Study. JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR)[Internet]. 2018;7(3 ):7-16. Available from: https://sid.ir/paper/245425/en

IEEE: Copy

M.R. SEDAGHAT, H. OSTADI MOGHADAM, F. ASKARIZADEH, F. NAROOIE NOORI, S. RAJABI, T. Rakhshandadi, and H. HASHEMIAN, “Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’ s Striae: A Contralateral Eye Study,” JOURNAL OF PARAMEDICAL SCIENCE AND REHABILITATION (JPSR), vol. 7, no. 3 , pp. 7–16, 2018, [Online]. Available: https://sid.ir/paper/245425/en

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