EFFECT OF OMEGA-3 FATTY ACIDS ON TESTOSTERONE PLASMA LEVEL IN WISTAR RAT

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JOKAR A.; TVAKOLI SARVESTANI F.; CHANGIZI ASHTIYANI S.; ZAREI A.; RAMEZANI M.; AGHABABA H.

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Journal: Alborz University Medical Journal Year:2016 | Volume:5 | Issue:1 Page(s): 28-33

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Title

EFFECT OF OMEGA-3 FATTY ACIDS ON TESTOSTERONE PLASMA LEVEL IN WISTAR RAT

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Keywords

OMEGAQ2

3Q3

FISH OILQ2

TESTOSTERONEQ2

LHQ2

Abstract

Background and Aims: High prevalence of infertility and many related problems has become a big problem for economy and healthy. This study is to determine the effect of dietary OMEGA-3 based on hypothalamic–pituitary-gonadal axis (HPG) activity and TESTOSTERONE plasma level in adult male adult wistar rat.Methods: This experimental study was conducted on 40 adult male wistar rats. Animals were with an average weight of 150±20 gr. They divided into five groups (n=8), including the control group, saline group and experimental group of minimum , average and maximum in which consumed dietary including OMEGA-3, 0.25 and 0.5 and 0.75 mg/kg dose the 29 days. The blood was take from the heart of animals. Using Radioimmunoassay methods, TESTOSTERONE and LH levels were measured. In this study effects of dietary OMEGA-3 on TESTOSTERONE secretion level in experimental groups, was compared with saline and control groups.Results: The results of a compared LH and TESTOSTERONE level with the control group (0.167±0.02 and 0.182±0.02) and all experimental groups, particularly at the maximum dose (0.654±0.09and 0.584±0.12 respectively), showed a significant increase.Conclusion: It was shown that the increase in OMEGA-3 plasma levels of in the experimental group led significantly increase in the TESTOSTERONE and LH level. This study showed that consumption of OMEGA-3 oils, significantly increase plasma levels of TESTOSTERONE and LH hormone.

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APA: Copy

JOKAR, A., TVAKOLI SARVESTANI, F., CHANGIZI ASHTIYANI, S., ZAREI, A., RAMEZANI, M., & AGHABABA, H.. (2016). EFFECT OF OMEGA-3 FATTY ACIDS ON TESTOSTERONE PLASMA LEVEL IN WISTAR RAT. ALBORZ UNIVERSITY MEDICAL JOURNAL, 5(1), 28-33. SID. https://sid.ir/paper/254389/en

Vancouver: Copy

JOKAR A., TVAKOLI SARVESTANI F., CHANGIZI ASHTIYANI S., ZAREI A., RAMEZANI M., AGHABABA H.. EFFECT OF OMEGA-3 FATTY ACIDS ON TESTOSTERONE PLASMA LEVEL IN WISTAR RAT. ALBORZ UNIVERSITY MEDICAL JOURNAL[Internet]. 2016;5(1):28-33. Available from: https://sid.ir/paper/254389/en

IEEE: Copy

A. JOKAR, F. TVAKOLI SARVESTANI, S. CHANGIZI ASHTIYANI, A. ZAREI, M. RAMEZANI, and H. AGHABABA, “EFFECT OF OMEGA-3 FATTY ACIDS ON TESTOSTERONE PLASMA LEVEL IN WISTAR RAT,” ALBORZ UNIVERSITY MEDICAL JOURNAL, vol. 5, no. 1, pp. 28–33, 2016, [Online]. Available: https://sid.ir/paper/254389/en

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