IMMUNOMODULATORY ROLE OF MESENCHYMAL STEM CELLS AGAINST MULTIPLE SCLEROSIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHAEMI AMIR; BABAEI ABRAKI SHAHNAZ; GHASEMI SEDIGHEH; SAJADIAN AZADEH; TOGHA MANSOUREH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Neuroscience Journal of Shefaye Khatam Year:2014 | Volume:2 | Issue:4 Page(s): 60-70

Download Full-Text

Persian Verion

View:

1,011

Download:

Cites:

Information Journal Paper

Title

IMMUNOMODULATORY ROLE OF MESENCHYMAL STEM CELLS AGAINST MULTIPLE SCLEROSIS

Author(s)

Keywords

CELL- AND TISSUE-BASED THERAPYQ3

IMMUNOMODULATIONQ3

MULTIPLE SCLEROSISQ3

MESENCHYMAL STROMAL CELLSQ3

Abstract

Introduction: MULTIPLE SCLEROSIS (MS) is an autoimmune disease of central nervous system that is characterized by the progressive loss of myelin. In addition to immunoregulatory properties, novel MS therapies promote myelin repair activities. Mesenchymal stem cells (MSCs) have been viewed as a potent tool for regenerative and immunosuppressive functions, indicating a potential therapy for MS. MSCs have immunological functions which are exerted by direct cell-to-cell contacts, secretion of stimulatory and inhibitory cytokines, and/or a combination of both mechanisms. Therefore, these cells can inhibit differentiation and proliferation of T-cell and stimulate the Th2 and regulatory T-cells through inhibitory effects on the immune system.Conclusion: In the current review, we discuss the mechanisms underlying the immunomodulatory effect of MSCs in different experimental models of MS.

Cites

No record.

References

No record.

Cite

APA: Copy

GHAEMI, AMIR, BABAEI ABRAKI, SHAHNAZ, GHASEMI, SEDIGHEH, SAJADIAN, AZADEH, & TOGHA, MANSOUREH. (2014). IMMUNOMODULATORY ROLE OF MESENCHYMAL STEM CELLS AGAINST MULTIPLE SCLEROSIS. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, 2(4), 60-70. SID. https://sid.ir/paper/258133/en

Vancouver: Copy

GHAEMI AMIR, BABAEI ABRAKI SHAHNAZ, GHASEMI SEDIGHEH, SAJADIAN AZADEH, TOGHA MANSOUREH. IMMUNOMODULATORY ROLE OF MESENCHYMAL STEM CELLS AGAINST MULTIPLE SCLEROSIS. NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM[Internet]. 2014;2(4):60-70. Available from: https://sid.ir/paper/258133/en

IEEE: Copy

AMIR GHAEMI, SHAHNAZ BABAEI ABRAKI, SEDIGHEH GHASEMI, AZADEH SAJADIAN, and MANSOUREH TOGHA, “IMMUNOMODULATORY ROLE OF MESENCHYMAL STEM CELLS AGAINST MULTIPLE SCLEROSIS,” NEUROSCIENCE JOURNAL OF SHEFAYE KHATAM, vol. 2, no. 4, pp. 60–70, 2014, [Online]. Available: https://sid.ir/paper/258133/en

Related Journal Papers