COMPARATIVE STUDY OF ANTINOCICEPTIVE EFFECTS OF MAGNESIUM SULFATE AND LIDOCAINE INTRA AND POSTOPERATIVE SURGERY IN ANIMAL MODEL

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Hajighahramani Shahin

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Title

COMPARATIVE STUDY OF ANTINOCICEPTIVE EFFECTS OF MAGNESIUM SULFATE AND LIDOCAINE INTRA AND POSTOPERATIVE SURGERY IN ANIMAL MODEL

Author(s)

Hajighahramani Shahin | Issue Writer Certificate

Keywords

MAGNESIUM SULFATEQ2

LIDOCAINEQ2

ANALGESIAQ3

DOGQ3

SURGERYQ2

Abstract

Introduction: The aim of the present study was to evaluate the antinociceptive efficacy of three lumbosacral analgesic protocols for elective tail ducking SURGERY in DOGs received acepromazine premedication.Materials and methods: 15 DOGs were randomly divided in 3 groups. Evaluated treatments were LIDOCAINE (4 mg/kg) alone (group 1), magnesium sulphate (2.5 mg/kg) in combination with LIDOCAINE (4 mg/kg) (group 2) and magnesium sulphate (2.5 mg/kg) alone (group 3) that were injected in the epidural space. ANALGESIA was assessed before surgical procedure using Von Frey device. ANALGESIA was evaluated during and after SURGERY, too.Results: The decrease of pain was significant in three treated groups during and after SURGERY (P<0.05). Pain score was lower in first and second groups than in the third group, during SURGERY. There was a difference in pain score between first and second groups in postoperative evaluation (P<0.05).Von Frey filaments evaluation showed that no significant changes in Von Frey thresholds were observed among the groups.Conclusion: Based on the present results it is concluded that MAGNESIUM SULFATE injected into the lumbosacral epidural space of DOGs causes to an antinociceptive effect in A d and C- fibers without any motor functional deficits. Additionally, MAGNESIUM SULFATE- LIDOCAINE combination produce suitable postoperative ANALGESIA.

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APA: Copy

Hajighahramani, Shahin. (2017). COMPARATIVE STUDY OF ANTINOCICEPTIVE EFFECTS OF MAGNESIUM SULFATE AND LIDOCAINE INTRA AND POSTOPERATIVE SURGERY IN ANIMAL MODEL. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, 5(3 (16) ), 47-62. SID. https://sid.ir/paper/264439/en

Vancouver: Copy

Hajighahramani Shahin. COMPARATIVE STUDY OF ANTINOCICEPTIVE EFFECTS OF MAGNESIUM SULFATE AND LIDOCAINE INTRA AND POSTOPERATIVE SURGERY IN ANIMAL MODEL. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;5(3 (16) ):47-62. Available from: https://sid.ir/paper/264439/en

IEEE: Copy

Shahin Hajighahramani, “COMPARATIVE STUDY OF ANTINOCICEPTIVE EFFECTS OF MAGNESIUM SULFATE AND LIDOCAINE INTRA AND POSTOPERATIVE SURGERY IN ANIMAL MODEL,” JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, vol. 5, no. 3 (16) , pp. 47–62, 2017, [Online]. Available: https://sid.ir/paper/264439/en

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