EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONIST (BUSERELIN) ON DEVELOPMENT OF OVARIAN FOLLICLES OF ADULT RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

PEIROUVI TAHMINEH; MOHAMMADBEIGI HADIS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES Year:2016 | Volume:4 | Issue:2 Page(s): 49-57

Download Full-Text

Persian Verion

View:

939

Download:

Cites:

Information Journal Paper

Title

EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONIST (BUSERELIN) ON DEVELOPMENT OF OVARIAN FOLLICLES OF ADULT RATS

Author(s)

PEIROUVI TAHMINEH | MOHAMMADBEIGI HADIS | Issue Writer Certificate

Keywords

OVARYQ2

BUSERELINQ2

GNRHQ1

FOLLICLESQ2

RATQ2

Abstract

Introduction and Aims: Nowadays, GNRH agonist like BUSERELIN acetate was used for treatment of infertility witch causes development of ovarian FOLLICLES. The purpose of this study was to investigate effects of BUSERELIN on the FOLLICLES development of OVARY.Materials and Methods: In this experimental interventional study, 24 adult female Wistar RATs were randomly divided into 3 groups (n=8). First and second treated groups received 300 mg/kg and 600 mg/kg BUSERELIN for 5 days respectively. Control group received normal saline the same times. BUSERELIN administrated subcutaneously. One month after first administration, the RATs were anesthetized with a lethal dose of chloroform and ovaries were removed. After fixation and routine Tissue Processing specimens were sectioned into 5 m thickness and then were stained with Hematoxilin and Eosin. Data were analyzed in GraphPad Prism 6 v 6.01 for windows, GraphPad Software using One Way ANOVA and Tukey test.P<0.05 was statistically considered significant.Results: The mean of multilaminar FOLLICLES class I decreased significantly in the second and first treated groups compared with the control group (P=0.018, P=0.012, respectively). Also, mean of multilaminar FOLLICLES class II decreased significantly in second and first treated groups compared with the control group (P=0.031, P=0.005, respectively).Conclusion: Our findings suggest short-term administration of high dose BUSERELIN inhibits development of FOLLICLES in RAT OVARY.

Cites

No record.

References

No record.

Cite

APA: Copy

PEIROUVI, TAHMINEH, & MOHAMMADBEIGI, HADIS. (2016). EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONIST (BUSERELIN) ON DEVELOPMENT OF OVARIAN FOLLICLES OF ADULT RATS. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, 4(2 ), 49-57. SID. https://sid.ir/paper/264456/en

Vancouver: Copy

PEIROUVI TAHMINEH, MOHAMMADBEIGI HADIS. EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONIST (BUSERELIN) ON DEVELOPMENT OF OVARIAN FOLLICLES OF ADULT RATS. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;4(2 ):49-57. Available from: https://sid.ir/paper/264456/en

IEEE: Copy

TAHMINEH PEIROUVI, and HADIS MOHAMMADBEIGI, “EFFECTS OF GONADOTROPIN RELEASING HORMONE AGONIST (BUSERELIN) ON DEVELOPMENT OF OVARIAN FOLLICLES OF ADULT RATS,” JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, vol. 4, no. 2 , pp. 49–57, 2016, [Online]. Available: https://sid.ir/paper/264456/en

Related Journal Papers