The effect of treadmill aerobic exercise training on adipolin, glucose and insulin in type 2 diabetic male rats

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Rahimpour Rahim; MEHRABANI JAVAD

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Journal: JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY Year:2018 | Volume:5 | Issue:1 Page(s): 93-105

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Title

The effect of treadmill aerobic exercise training on adipolin, glucose and insulin in type 2 diabetic male rats

Author(s)

Rahimpour Rahim | MEHRABANI JAVAD | Issue Writer Certificate

Keywords

Aerobic training

Adipolin

Insulin resistance

Type 2 diabetes

Abstract

Secretion of pro-inflammatory and anti-inflammatory cytokines play a critical role in the regulation of metabolic conditions. This study examines the effect of eight weeks Aerobic training on Adipolin cytokine and Insulin resistance index in type 2 diabetic male rats. Eighteen 8-10 weeks Wister rats with 200-220 gr are selected and they equally divided into two diabetes [DBT] and control [CON] groups randomly. The training program includes 8 weeks of endurance training on a treadmill at a constant dip of 5%. The speed started from 10 meters per minute and it rised to the 25 meters per minute and its time started from 15 minutes to 45 minutes. In end of 8 weeks training, blood samples were taken after 12 hours of fasting in order to determination of insulin, glucose and Adipolin levels. The homeostatic model assessment [HOMA] was calculated as Insulin resistance index. The data were analyzed using the independent t test with the SPSS software ver. 16. A significant increase was observed in Adipolin (1. 36± 0. 054 vs. 1. 11± 0. 065 ng/ml; p=0. 002) level, and while observing significant decreases in connection with glucose (276. 88± 27. 59 vs. 324. 55± 16. 04 mg/dl; p=0. 001), insulin (0. 206± 0. 02 vs. 0. 235± 0. 02 mU/l; p=0. 033) and Insulin resistance (2. 55± 0. 495 vs. 3. 40± 0. 468 mg/dl; p=0. 002). It seems that Aerobic training with moderate intensity could decrease Insulin resistance with increasing serum levels of Adipolin in type 2 diabetic rats.

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APA: Copy

Rahimpour, Rahim, & MEHRABANI, JAVAD. (2018). The effect of treadmill aerobic exercise training on adipolin, glucose and insulin in type 2 diabetic male rats. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, 5(1 ), 93-105. SID. https://sid.ir/paper/269311/en

Vancouver: Copy

Rahimpour Rahim, MEHRABANI JAVAD. The effect of treadmill aerobic exercise training on adipolin, glucose and insulin in type 2 diabetic male rats. JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY[Internet]. 2018;5(1 ):93-105. Available from: https://sid.ir/paper/269311/en

IEEE: Copy

Rahim Rahimpour, and JAVAD MEHRABANI, “The effect of treadmill aerobic exercise training on adipolin, glucose and insulin in type 2 diabetic male rats,” JOURNAL OF APPLIED HEALTH STUDIES IN SPORT PHYSIOLOGY, vol. 5, no. 1 , pp. 93–105, 2018, [Online]. Available: https://sid.ir/paper/269311/en

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