P53 PROTEIN IN SERUM AND URINE SAMPLES OF PATIENTS WITH BLADDER TRANSITIONAL CELL CARCINOMA AND ITS OVEREXPRESSION IN TUMORAL TISSUE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

DARABI M.R.; TAYEBI MEYBODI N.; MAHDAVI R.; ARAB D.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: UROLOGY JOURNAL Year:2006 | Volume:3 | Issue:4 Page(s): 216-219

Download Full-Text

View:

314

Download:

Cites:

Information Journal Paper

Title

P53 PROTEIN IN SERUM AND URINE SAMPLES OF PATIENTS WITH BLADDER TRANSITIONAL CELL CARCINOMA AND ITS OVEREXPRESSION IN TUMORAL TISSUE

Author(s)

DARABI M.R. | TAYEBI MEYBODI N. | MAHDAVI R. | ARAB D. | Issue Writer Certificate

Keywords

P53 PROTEIN

TP53

BLADDER CANCERS

ENZYME-LINKED IMMUNOSORBENT ASSAY

IMMUNOHISTOCHEMISTRY

Abstract

Introduction: The aim of this study was to evaluate the levels of P53 PROTEIN in serum and urine samples of patients with bladder transitional cell carcinoma (TCC) and their relation with the overexpression of p53 in the tumoral tissue. Materials and Methods: A total of 39 patients with bladder TCC were evaluated for P53 PROTEIN in their serum and urine samples and the overexpression of this marker in their tumoral tissue.Results: Of 39 patients with bladder TCC, 29 (74.4%) had tissue specimens positive for P53 PROTEIN overexpression, 20 (51.3%) had P53 PROTEIN in their serum samples, and 27 (69.2%) had this protein in their urine samples. A positive immunohistochemical finding was more common in higher grades of the bladder tumor (P = .03), but not in higher stages (P=.07). Eighteen of 20 patients (90%) with a positive serum for p53 showed protein overexpression in the tumoral tissue of the bladder (P =.03). Of 27 patients with a positive urine sample, 25 (92.6%) had p53 overexpression in their bladder tissue, and of the remainder 12 patients with a negative P53 PROTEIN in their urine samples, 8 (66.7%) had no evidence of P53 PROTEIN overexpression in their tumoral tissue (P<.001). The grade and stage of tumor had no correlation with serum or urinary p53.Conclusion: According to our findings, a positive serum or urine sample for P53 PROTEIN is highly associated with the overexpression of P53 PROTEIN in the tumoral tissue of patients with bladder TCC.

Cites

No record.

References

No record.

Cite

APA: Copy

DARABI, M.R., TAYEBI MEYBODI, N., MAHDAVI, R., & ARAB, D.. (2006). P53 PROTEIN IN SERUM AND URINE SAMPLES OF PATIENTS WITH BLADDER TRANSITIONAL CELL CARCINOMA AND ITS OVEREXPRESSION IN TUMORAL TISSUE. UROLOGY JOURNAL, 3(4), 216-219. SID. https://sid.ir/paper/270740/en

Vancouver: Copy

DARABI M.R., TAYEBI MEYBODI N., MAHDAVI R., ARAB D.. P53 PROTEIN IN SERUM AND URINE SAMPLES OF PATIENTS WITH BLADDER TRANSITIONAL CELL CARCINOMA AND ITS OVEREXPRESSION IN TUMORAL TISSUE. UROLOGY JOURNAL[Internet]. 2006;3(4):216-219. Available from: https://sid.ir/paper/270740/en

IEEE: Copy

M.R. DARABI, N. TAYEBI MEYBODI, R. MAHDAVI, and D. ARAB, “P53 PROTEIN IN SERUM AND URINE SAMPLES OF PATIENTS WITH BLADDER TRANSITIONAL CELL CARCINOMA AND ITS OVEREXPRESSION IN TUMORAL TISSUE,” UROLOGY JOURNAL, vol. 3, no. 4, pp. 216–219, 2006, [Online]. Available: https://sid.ir/paper/270740/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops