مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

227
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

100
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

A Significant Upregulation of miR-886-5p in High Grade and Invasive Bladder Tumors

Pages

  2160-2164

Abstract

 Purpose: To investigate the expression alteration of miR-886-5p in bladder tumors and evaluating its expression level as a potential biomarker in this type of cancer. Materials and Methods: Formalin-fixed paraffin-embedded (FFPE) samples of bladder tumors belonging to 70 patients whom had been referred to the Shahid Labbafi-Nejad medical center were obtained from the archival collection of pathology department. After RNA extraction and cDNA synthesis, expression levels of miR-886-5p were quantified by a real-time reverse transcription polymerase chain reaction (RT-PCR) approach. Results: Our data revealed a significant upregulation (~3 times) of miR-886-5p in high grade bladder tumors, compared to the low grade ones (P <. 05). Moreover, its expression level could significantly discriminate noninvasive (Ta, T1) from invasive (T2-T4) tumor stages. Conclusion: Our data suggests a potential role for miR-886-5p in progression of bladder cancer.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Khoshnevisan, Atefeh, PARVIN, MAHMOUD, GHORBANMEHR, NASIM, Hatefi, Nasim, GALEHDARI, HAMID, Mohsen Ziaee, Seyed Amir, & MOWLA, SEYED JAVAD. (2015). A Significant Upregulation of miR-886-5p in High Grade and Invasive Bladder Tumors. UROLOGY JOURNAL, 12(3), 2160-2164. SID. https://sid.ir/paper/271040/en

    Vancouver: Copy

    Khoshnevisan Atefeh, PARVIN MAHMOUD, GHORBANMEHR NASIM, Hatefi Nasim, GALEHDARI HAMID, Mohsen Ziaee Seyed Amir, MOWLA SEYED JAVAD. A Significant Upregulation of miR-886-5p in High Grade and Invasive Bladder Tumors. UROLOGY JOURNAL[Internet]. 2015;12(3):2160-2164. Available from: https://sid.ir/paper/271040/en

    IEEE: Copy

    Atefeh Khoshnevisan, MAHMOUD PARVIN, NASIM GHORBANMEHR, Nasim Hatefi, HAMID GALEHDARI, Seyed Amir Mohsen Ziaee, and SEYED JAVAD MOWLA, “A Significant Upregulation of miR-886-5p in High Grade and Invasive Bladder Tumors,” UROLOGY JOURNAL, vol. 12, no. 3, pp. 2160–2164, 2015, [Online]. Available: https://sid.ir/paper/271040/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button