مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

187
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

108
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

The Protective Effects of Pulsed Magnetic Field and Melatonin on Testis Torsion and Detorsion Induced Rats Indicated by Scintigraphy, Positron Emission Tomography/Computed Tomography and Histopathological Methods

Pages

  0-0

Abstract

 Purpose: The aim of the present study was to show the protective effect of pulsed magnetic field (PMF) application and melatonin administration on damage in testis in a one-sided torsion detorsion induced rat model using testicular scintigraphy with 99mTc pertechnetate, PET/CT with 18F-FDG and histopathological methods. Materials and Methods: Sixty male rats were used in the study; 30 rats were randomly divided into five groups for one day applications of sham control, torsion, melatonin, pulsed magnetic field (PMF) and melatonin plus PMF. Similarly, the other 30 rats were divided into the same five groups (n = 6) for one week treatment, but the animals were sacrificed after one week. Rats were exposed to 50 Hz, 1 mT PMF for two hours. PET/CT with 37 MBq 18F-FDG and testicular scintigraphy with and 37 MBq 99mTc pertechnetate examinations were carried out, and testicular tissue was examined using histopathological methods. Results: In one day treatment, melatonin administration significantly increased perfusion and glucose metabolism compared to torsion group (P < 0. 01). Perfusion and glucose metabolism was also higher in the PMF and melatonin plus PMF groups than torsion group (P < 0. 01). In one week treatment, melatonin administration resulted in a significantly higher perfusion and glucose metabolism rates compared to torsion group (P < 0. 01 and P < 0. 001, respectively). In addition, perfusion and glucose metabolism significantly increased in PMF and melatonin plus PMF groups compared to torsion group (P < 0. 01 and P < 0. 001, respectively). Furthermore, caspase-3 immunoreactivity and pathological changes increased in the torsion group (P < 0. 05). Melatonin and melatonin plus PMF treatment reduced the rate of immunoreactivity and pathological findings compared to the torsion group (P < 0. 05). Conclusion: According to these results it can be concluded that PMF application has a therapeutic benefit as effective as melatonin administering. In addition, it was indicated that PET/CT with 18F-FDG and testicular scintigraphy with 99mTc pertechnetate could be efficiently used in determining the treatment efficiency in testicular torsion.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Gul, Serdar Savas, Gurgul, Serkan, Uysal, Murat, & Erdemir, Fikret. (2018). The Protective Effects of Pulsed Magnetic Field and Melatonin on Testis Torsion and Detorsion Induced Rats Indicated by Scintigraphy, Positron Emission Tomography/Computed Tomography and Histopathological Methods. UROLOGY JOURNAL, 15(6), 0-0. SID. https://sid.ir/paper/271251/en

    Vancouver: Copy

    Gul Serdar Savas, Gurgul Serkan, Uysal Murat, Erdemir Fikret. The Protective Effects of Pulsed Magnetic Field and Melatonin on Testis Torsion and Detorsion Induced Rats Indicated by Scintigraphy, Positron Emission Tomography/Computed Tomography and Histopathological Methods. UROLOGY JOURNAL[Internet]. 2018;15(6):0-0. Available from: https://sid.ir/paper/271251/en

    IEEE: Copy

    Serdar Savas Gul, Serkan Gurgul, Murat Uysal, and Fikret Erdemir, “The Protective Effects of Pulsed Magnetic Field and Melatonin on Testis Torsion and Detorsion Induced Rats Indicated by Scintigraphy, Positron Emission Tomography/Computed Tomography and Histopathological Methods,” UROLOGY JOURNAL, vol. 15, no. 6, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/271251/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button