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Information Journal Paper

Title

Therapeutic Effects of Aqueous Extracts of Cerasus Avium Stem on Ethylene Glycol-Induced Kidney Calculi in Rats

Pages

  4024-4029

Abstract

 Purpose: To investigate the therapeutic effects of the aqueous extract of Cerasus Avium stem on kidney calculi. Materials and Methods: In this experimental study, forty-eight (48) male Wistar rats were randomly allocated into six (6) groups and were studied during a 30 day period. Group A served as normal control and Group B received 1% ethylene glycol in drinking water (EG group). C, D, E, and F Groups, received 1% ethylene glycol from day 1 and were used as prevention and treatment subjects. Rats in prevention groups of low dose (C) and high dose (D) extract, were gavaged with 200 and 400 mg/kg extract respectively from first day of the experiment and treatment groups of low dose (E) and high dose (F) extract, were gavaged with 200 and 400 mg/kg extract respectively from the 15th day of the experiment. Results: On the 30th days of the experiment, serum level of magnesium and potassium decreased significantly in EG group compared with A, C, D, E and F groups (P <. 05), while serum level of calcium, creatinine, uric acid, sodium and urine level of calcium, creatinine, uric acid, increased significantly in EG group compared with A, C, D, E and F groups (P <. 05). In the prevention and treatment groups, the number of deposits decreased significantly compared with EG group on the 30th day (P <. 05). Conclusion: Cerasus Avium stem has a therapeutic effect on calcium oxalate stones in rats with nephrolithiasis and reduces the number of calcium oxalate deposits.

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    APA: Copy

    Azaryan, Ehsaneh, MALEKANEH, MOHAMMAD, Shemshadi nejad, Maryam, & HAGHIGHI, FATEMEH. (2017). Therapeutic Effects of Aqueous Extracts of Cerasus Avium Stem on Ethylene Glycol-Induced Kidney Calculi in Rats. UROLOGY JOURNAL, 14(4), 4024-4029. SID. https://sid.ir/paper/271526/en

    Vancouver: Copy

    Azaryan Ehsaneh, MALEKANEH MOHAMMAD, Shemshadi nejad Maryam, HAGHIGHI FATEMEH. Therapeutic Effects of Aqueous Extracts of Cerasus Avium Stem on Ethylene Glycol-Induced Kidney Calculi in Rats. UROLOGY JOURNAL[Internet]. 2017;14(4):4024-4029. Available from: https://sid.ir/paper/271526/en

    IEEE: Copy

    Ehsaneh Azaryan, MOHAMMAD MALEKANEH, Maryam Shemshadi nejad, and FATEMEH HAGHIGHI, “Therapeutic Effects of Aqueous Extracts of Cerasus Avium Stem on Ethylene Glycol-Induced Kidney Calculi in Rats,” UROLOGY JOURNAL, vol. 14, no. 4, pp. 4024–4029, 2017, [Online]. Available: https://sid.ir/paper/271526/en

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