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Information Journal Paper

Title

UROLOGICAL ONCOLOGY: Effect of Treatment Modality on Long Term Renal Functions in Patients With Muscle Invasive Bladder Cancer

Pages

  274-278

Abstract

 Purpose: To compare of changes in glomerular filtration rate (GFR) in patients who underwent radical cystectomy (RC) and multimodal treatment (MMT). Materials and Methods: We identified 472 consecutive patients who underwent RC or treated with MMT for muscle invasive bladder cancer (MIBC) at our institution, between January 1995 and December 2010. After excluding the patients who died within 5 years or without 5 years of follow-up, 175 and 59 patients who were treated with RC and MMT, respectively were included to the study. GFR was measured before treatment and every 6 months after treatment till the end of 60th month. Results: The mean age and mean baseline GFR were 66. 5± 5. 7 years and 85. 1± 18. 2 mL/min/1. 73m2, respectively for all patients. We detected statistically significant higher decrease rates for GFRs in MMT group compared to RC group at every follow up period till 42nd month. Renal function decreasing was found to be more prominent during first year of follow-up (79. 1 to 65. 9 mL/min/1. 73m2) in MMT group. However, GFR decreased more regularly in RC group (~4 mL/min/1. 73m2 per year). MMT, lower baseline GFR, Diabetes Mellitus, hypertension, and ureteroenteric anastomotic stricture development were associated with low GFR under 60 and 45 mL/min at the end of five years. Conclusion: Decreased renal function is noted in many MIBC patients after RC or MMT in the long-term follow-up. Renal function deterioration is more prominent within the first year after MMT.

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    Cite

    APA: Copy

    Hamidi, Nurullah, Suer, Evren, Ozkidik, Mete, Gokce, Mehmet Ilker, ozturk, Erdem, Ozcan, Cihat, Turkolmez, Kadir, Baltaci, Sumer, & Beduk, Yasar. (2019). UROLOGICAL ONCOLOGY: Effect of Treatment Modality on Long Term Renal Functions in Patients With Muscle Invasive Bladder Cancer. UROLOGY JOURNAL, 16(3), 274-278. SID. https://sid.ir/paper/271561/en

    Vancouver: Copy

    Hamidi Nurullah, Suer Evren, Ozkidik Mete, Gokce Mehmet Ilker, ozturk Erdem, Ozcan Cihat, Turkolmez Kadir, Baltaci Sumer, Beduk Yasar. UROLOGICAL ONCOLOGY: Effect of Treatment Modality on Long Term Renal Functions in Patients With Muscle Invasive Bladder Cancer. UROLOGY JOURNAL[Internet]. 2019;16(3):274-278. Available from: https://sid.ir/paper/271561/en

    IEEE: Copy

    Nurullah Hamidi, Evren Suer, Mete Ozkidik, Mehmet Ilker Gokce, Erdem ozturk, Cihat Ozcan, Kadir Turkolmez, Sumer Baltaci, and Yasar Beduk, “UROLOGICAL ONCOLOGY: Effect of Treatment Modality on Long Term Renal Functions in Patients With Muscle Invasive Bladder Cancer,” UROLOGY JOURNAL, vol. 16, no. 3, pp. 274–278, 2019, [Online]. Available: https://sid.ir/paper/271561/en

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