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Information Journal Paper

Title

RELATIONSHIP BETWEEN SERUM AMINOTRANSFERASE LEVELS ANDMETABOLIC DISORDERS IN NORTHERN CHINA

Pages

  15-26

Abstract

 Background: Increasing evidence suggests an association between elevated serum aminotransferase levels and metabolic disorders (metabolic syndrome, hyperlipemia and diabetes mellitus). However, the significance of relatively low levels of aminotransferases in relation to metabolic disorders has not been fully investigated in the general population. We investigated the association between serum amiontransferase levels and metabolic disorders using data from a survey in Jilin province, China.Methods: In 2007, a survey was conducted throughout Jilin, China, covering both urban and rural areas. A total of 3835 people, 18 to 79 years old including 1761 men and 2074 women, underwent real-time ULTRASONOGRAPHY, blood tests including aspartate aminotransferase and ALANINE AMINOTRANSFERASE, and had interviews with a structured questionnaire.Results: Serum aminotransferase levels within the normal range were associated with METABOLIC SYNDROME independent of age, occupation, cultural and educational level, income, body mass index, waist circumference, smoking, and alcohol intake. Compared with the lowest level (<20 IU/L), the adjusted odds ratios for ALT levels of 20-29, 30-39, 40-49 and >50 IU/L were 1.92, 2.50, 2.97, and 3.52 in men, and 1.38, 1.54, 3.06, and 2.62 in women, respectively. Near-normal serum aminotransferase levels associated with hyperlipemia, NAFLD, DMwere also found in the study.Conclusions: Normal to near-normal serum aminotransferase levels are associated with metabolic disorders. Serum ALT levels of 21-25 IU/L for men, and 17-22 IU/L for women are suggested as CUTOFF LEVELS that detect metabolic disorders affecting the liver.

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    APA: Copy

    ZHANG, H., DING, YH, LI, QM, SUN, J., HE, SM, FENG, XW, ZHAO, YL, ZHOU, XJ, CAI, YJ, WANG, C., SHI, XD, WANG, ZF, ZHOU, Q., & NIU, JQ. (2012). RELATIONSHIP BETWEEN SERUM AMINOTRANSFERASE LEVELS ANDMETABOLIC DISORDERS IN NORTHERN CHINA. IRANIAN JOURNAL OF PUBLIC HEALTH, 41(2), 15-26. SID. https://sid.ir/paper/272894/en

    Vancouver: Copy

    ZHANG H., DING YH, LI QM, SUN J., HE SM, FENG XW, ZHAO YL, ZHOU XJ, CAI YJ, WANG C., SHI XD, WANG ZF, ZHOU Q., NIU JQ. RELATIONSHIP BETWEEN SERUM AMINOTRANSFERASE LEVELS ANDMETABOLIC DISORDERS IN NORTHERN CHINA. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2012;41(2):15-26. Available from: https://sid.ir/paper/272894/en

    IEEE: Copy

    H. ZHANG, YH DING, QM LI, J. SUN, SM HE, XW FENG, YL ZHAO, XJ ZHOU, YJ CAI, C. WANG, XD SHI, ZF WANG, Q. ZHOU, and JQ NIU, “RELATIONSHIP BETWEEN SERUM AMINOTRANSFERASE LEVELS ANDMETABOLIC DISORDERS IN NORTHERN CHINA,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 41, no. 2, pp. 15–26, 2012, [Online]. Available: https://sid.ir/paper/272894/en

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