USE OF NONINSULIN ANTI DIABETICS FOR PREVENTION AND TREATMENT OF CANCER- NARRATIVE REVIEW ARTICLE

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RAANA SADAF; JAVEED AQEEL

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Public Health Year:2015 | Volume:44 | Issue:2 Page(s): 176-184

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Information Journal Paper

Title

USE OF NONINSULIN ANTI DIABETICS FOR PREVENTION AND TREATMENT OF CANCER- NARRATIVE REVIEW ARTICLE

Author(s)

RAANA SADAF | JAVEED AQEEL | Issue Writer Certificate

Keywords

DIABETES

MORTALITY

METFORMIN HYPERINSULINEMIA

MALIGNANT

HYPERINSULINEMIA

THIAZOLIDINEDIONES

Abstract

Background: Epidemiological evidence shows that cancer and DIABETES are major causes of death in the world. Type2 DIABETES increases the risk of cancer-specific MORTALITY. This review relates diabetic therapies, DIABETES and cancer.Method: All published papers in this field were searched, looking into such databases as Science Direct, ISI Web of Knowledge, PubMed and Scopus.Results: In cancer patients, metformin improves patient outcome and reduces cancer risk. Sulfonylureas may increase risk of cancer, but decreased risk of cancer is associated with THIAZOLIDINEDIONES in type2 diabetic subjects. Metformin lowers circulating insulin and it may be important for treatment of HYPERINSULINEMIA-associated cancers, such as colon and breast cancer.Conclusion: However, laboratory investigations and large-scale population based studies are required for further in-vestigation of association of cancer-preventive, anti-cancer and cancer-mortality of noninsulin antidiabetics.

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APA: Copy

RAANA, SADAF, & JAVEED, AQEEL. (2015). USE OF NONINSULIN ANTI DIABETICS FOR PREVENTION AND TREATMENT OF CANCER- NARRATIVE REVIEW ARTICLE. IRANIAN JOURNAL OF PUBLIC HEALTH, 44(2), 176-184. SID. https://sid.ir/paper/273715/en

Vancouver: Copy

RAANA SADAF, JAVEED AQEEL. USE OF NONINSULIN ANTI DIABETICS FOR PREVENTION AND TREATMENT OF CANCER- NARRATIVE REVIEW ARTICLE. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2015;44(2):176-184. Available from: https://sid.ir/paper/273715/en

IEEE: Copy

SADAF RAANA, and AQEEL JAVEED, “USE OF NONINSULIN ANTI DIABETICS FOR PREVENTION AND TREATMENT OF CANCER- NARRATIVE REVIEW ARTICLE,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 44, no. 2, pp. 176–184, 2015, [Online]. Available: https://sid.ir/paper/273715/en

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