مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

287
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

159
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

ANALYSIS OF CHEMOKINE RECEPTOR GENE EXPRESSION IN ESOPHAGEAL CANCER CELLS COMPARED WITH BREAST CANCER WITH INSIGHTS INTO METASTASIS

Pages

  1353-1358

Abstract

 Background: CHEMOKINE RECEPTORS have been shown to play an important role in the development and metastatic spread of various malignancies. In this study, the gene expression profile of some key CHEMOKINE RECEPTORS involved in METASTASIS has been investigated in esophageal and BREAST CANCER cell lines.Methods: In a descriptive study, gene expression profile of CCR1, CCR6, CCR7, CCR9, CXCR1, and CXCR4 in hu-man ESOPHAGEAL CANCER cell line (KYSE-30) and human BREAST CANCER cell line (MCF7) were analyzed using real-time PCR and their results were compared accordingly.Results: We demonstrated for the first time the expression of CCR1, CCR6, CCR7, CCR9, CXCR1, and CXCR4 at transcriptional level in human ESOPHAGEAL CANCER cell line. The expression of CCR1, CCR7 and CXCR4 were lower in esophageal compared with BREAST CANCER cells, although without significant difference. CCR9 was highly expressed in ESOPHAGEAL CANCER cells as compared to the BREAST CANCER cells (P<0.05). Similarly, the expression of CCR6 and CXCR1 were higher, although without significant difference.Conclusion: ESOPHAGEAL CANCER cells like BREAST CANCER express some key CHEMOKINE RECEPTORS involved in METASTASIS. Targeting of proposed receptors in ESOPHAGEAL CANCER may be a novel strategy for prevention of cancer METASTASIS.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    MISHAN, MOHAMMAD AMIR, HEIRANI TABASI, ASIEH, MOKHBERIAN, NEDA, HASANZADEH, MALIHEH, KALALIAN MOGHADDAM, HAMID, BAHRAMI, AHMAD REZA, & AHMADIANKIA, NAGHMEH. (2015). ANALYSIS OF CHEMOKINE RECEPTOR GENE EXPRESSION IN ESOPHAGEAL CANCER CELLS COMPARED WITH BREAST CANCER WITH INSIGHTS INTO METASTASIS. IRANIAN JOURNAL OF PUBLIC HEALTH, 44(10), 1353-1358. SID. https://sid.ir/paper/273816/en

    Vancouver: Copy

    MISHAN MOHAMMAD AMIR, HEIRANI TABASI ASIEH, MOKHBERIAN NEDA, HASANZADEH MALIHEH, KALALIAN MOGHADDAM HAMID, BAHRAMI AHMAD REZA, AHMADIANKIA NAGHMEH. ANALYSIS OF CHEMOKINE RECEPTOR GENE EXPRESSION IN ESOPHAGEAL CANCER CELLS COMPARED WITH BREAST CANCER WITH INSIGHTS INTO METASTASIS. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2015;44(10):1353-1358. Available from: https://sid.ir/paper/273816/en

    IEEE: Copy

    MOHAMMAD AMIR MISHAN, ASIEH HEIRANI TABASI, NEDA MOKHBERIAN, MALIHEH HASANZADEH, HAMID KALALIAN MOGHADDAM, AHMAD REZA BAHRAMI, and NAGHMEH AHMADIANKIA, “ANALYSIS OF CHEMOKINE RECEPTOR GENE EXPRESSION IN ESOPHAGEAL CANCER CELLS COMPARED WITH BREAST CANCER WITH INSIGHTS INTO METASTASIS,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 44, no. 10, pp. 1353–1358, 2015, [Online]. Available: https://sid.ir/paper/273816/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button