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Information Journal Paper

Title

APPLICATION OF FUZZY LOGIC IN ORAL CANCER RISK ASSESSMENT

Pages

  612-619

Abstract

 Background: The mapping of the malignization mechanism is still incomplete, but oxidative stress is strongly corre-lated to carcinogenesis. In our research, using FUZZY LOGIC, we aimed to estimate the oxidative stress related-cancerization risk of the ORAL POTENTIALLY MALIGNANT DISORDERS.Methods: Serum from 16 patients diagnosed (clinical and histopathological) with ORAL POTENTIALLY MALIGNANT DISORDERS (Dept. of Cranio-Maxillofacial Surgery and Radiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj Napoca, Romania) was processed fluorometric for MALONDIALDEHYDE and PROTON DONORS assays (Dept. of Physiolo-gy, "Iuliu Hațieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania). The values were used as inputs, they were associated linguistic terms using MIN-MAX method and 25 IF-THEN inference rules were generated to estimate the output value, the cancerization risk appreciated on a scale from 1 to 10 - IF MALONDIALDEHYDE is very high and donors protons are very low THEN the CANCER RISK is reaching the maximum value (Dept. of Industrial Engineer-ing, Faculty of Managerial and Technological Engineering, University of Oradea, Oradea, Romania) (2012-2014).Results: We estimated the cancerization risk of the ORAL POTENTIALLY MALIGNANT DISORDERS by implementing the multi-criteria decision support system based on serum MALONDIALDEHYDE and PROTON DONORS' values. The risk was estimated as a concrete numerical value on a scale from 1 to 10 depending on the input numerical/linguistic value.Conclusion: The multi-criteria decision support system proposed by us, integrated into a more complex compute-rized decision support system, could be used as an important aid in oral cancer screening and establish future medical decision in ORAL POTENTIALLY MALIGNANT DISORDERS.

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    APA: Copy

    SCROBOTA, IOANA, BACIUT, GRIGORE, FILIP, ADRIANA GABRIELA, TODOR, BIANCA, BLAGA, FLORIN, & BACIUT, MIHAELA FELICIA. (2017). APPLICATION OF FUZZY LOGIC IN ORAL CANCER RISK ASSESSMENT. IRANIAN JOURNAL OF PUBLIC HEALTH, 46(5), 612-619. SID. https://sid.ir/paper/274142/en

    Vancouver: Copy

    SCROBOTA IOANA, BACIUT GRIGORE, FILIP ADRIANA GABRIELA, TODOR BIANCA, BLAGA FLORIN, BACIUT MIHAELA FELICIA. APPLICATION OF FUZZY LOGIC IN ORAL CANCER RISK ASSESSMENT. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2017;46(5):612-619. Available from: https://sid.ir/paper/274142/en

    IEEE: Copy

    IOANA SCROBOTA, GRIGORE BACIUT, ADRIANA GABRIELA FILIP, BIANCA TODOR, FLORIN BLAGA, and MIHAELA FELICIA BACIUT, “APPLICATION OF FUZZY LOGIC IN ORAL CANCER RISK ASSESSMENT,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 46, no. 5, pp. 612–619, 2017, [Online]. Available: https://sid.ir/paper/274142/en

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