مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

PREVALENCE OF VIRULENCE FACTORS AND VANCOMYCIN-RESISTANT GENES AMONG ENTEROCOCCUS FAECALIS AND E. FAECIUM ISOLATED FROM CLIN-ICAL SPECIMENS

Pages

  806-813

Abstract

 Background: The aim of this study was to determine the occurrence of virulence determinants and vancomycin- resistant genes among Enterococcus faecalis and E. FAECIUM obtained from various clinical sources.Methods: The study was performed on the 280 enterococcal isolated from clinical specimens in Hamadan hospitals, western Iran in 2012-14. Antibiotic susceptibility testing was performed using disk diffusion and Minimal Inhibitory Concentration (MIC) methods. The presence of vancomycin-resistant genes and virulence genes was investigated using PCR.Results: Totally 280 enterococcal isolates were identified as follows: E. FAECALIS (62.5%), E. FAECIUM (24%) and Enterococ-cus spp (13.5%). The results of antibiotic susceptibility testing showed that resistance rates to vancomycin and teicoplanin in E. FAECALIS and E. FAECIUM isolates were 5% and 73%, respectively. Of Sixty VANCOMYCIN-RESISTANT ENTEROCOCCI strains, fifty-one isolates were identified as E. FAECIUM (VREfm) and nine as E. FAECALIS (VREfs). Prevalence of esp, hyl, and asa1 genes were determined as 82%, 71.6%, and 100%, respectively in E. FAECIUM strains; and 78%, 56.6%, and 97%, respectively in E. FAECALIS strains.Conclusion: The increased frequency of VREF, as seen with rapid rise in the number of vanA isolates should be con-sidered in infection control practices.

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    • Cite

    APA: Copy

    NASAJ, MONA. (2016). PREVALENCE OF VIRULENCE FACTORS AND VANCOMYCIN-RESISTANT GENES AMONG ENTEROCOCCUS FAECALIS AND E. FAECIUM ISOLATED FROM CLIN-ICAL SPECIMENS. IRANIAN JOURNAL OF PUBLIC HEALTH, 45(6), 806-813. SID. https://sid.ir/paper/274282/en

    Vancouver: Copy

    NASAJ MONA. PREVALENCE OF VIRULENCE FACTORS AND VANCOMYCIN-RESISTANT GENES AMONG ENTEROCOCCUS FAECALIS AND E. FAECIUM ISOLATED FROM CLIN-ICAL SPECIMENS. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2016;45(6):806-813. Available from: https://sid.ir/paper/274282/en

    IEEE: Copy

    MONA NASAJ, “PREVALENCE OF VIRULENCE FACTORS AND VANCOMYCIN-RESISTANT GENES AMONG ENTEROCOCCUS FAECALIS AND E. FAECIUM ISOLATED FROM CLIN-ICAL SPECIMENS,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 45, no. 6, pp. 806–813, 2016, [Online]. Available: https://sid.ir/paper/274282/en

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