Prevalence of Multidrug Resistance in Enterococcus faecium Isolated from Patients and Environment of Hospitals in Lorestan Province, (Iran)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GOUDARZI MANSOUR; MOHABATI MOBAREZ ASHRAF; NAJAR PEERAYEH SHAHIN; MIRZAEE MOHSEN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2018 | Volume:12 | Issue:5 Page(s): 71-78

Download Full-Text

Persian Verion

View:

565

Download:

Cites:

Information Journal Paper

Title

Prevalence of Multidrug Resistance in Enterococcus faecium Isolated from Patients and Environment of Hospitals in Lorestan Province, (Iran)

Author(s)

GOUDARZI MANSOUR | MOHABATI MOBAREZ ASHRAF | NAJAR PEERAYEH SHAHIN | MIRZAEE MOHSEN | Issue Writer Certificate

Keywords

Drug ResistanceQ1

MicrobialQ1

Enterococcous faeciumQ1

VancomycinQ1

Abstract

Background and Objectives: With increasing use of Vancomycin antibiotic, Vancomycin-resistant Enterococcus (VRE), is considered as a major cause of nosocomial infections. In this study, the pattern of antibiotic resistance and prevalence of Vancomycin resistant enterococcus faecium, were investigated. Methods: In this descriptive study, after isolation and identification of 690 strains of Enterococcus from clinical and environmental specimens in different wards of Lorestan hospitals, the pattern of antibiotic resistance of these strains to common antibiotics, were investigated using dick diffusion and agar dilution methods. The antibiotic resistance genes (vanA, vanB, pbp5, pbpZ, and blaZ), were detected by PCR technique. Results: Among 690 studied Enterococcus isolates, 439 isolates (64%), were Enterococcous feacalis, 228 isolates (33%) Enterococcous faecium, and 23 isolates (3%), were other Enterococci. Based on the antibiogram test by disk diffusion method, the highest resistance was to penicillin with 446 isolates (67%) and the lowest resistance was to linezolid with 0 isolate (0%). In the evaluation of resistance using minimum inhibitory concentration (MIC), the antibiotic resistance rate was obtained to be 58% for ampicillin, 59% for penicillin, and 23% for Vancomycin. Resistance genes, including vanA, vanB, pbp5, pbpZ, and blaZ, were detected in 84 (72%), 26 (22%), 87 (74%), 63 (53%), and 0 (0%) of the isolates. Conclusion: Based on the results of this study, resistance to Vancomycin in Enterococcus strains is also found in Lorestan province like other parts of the world. Therefore, application of control and preventive measures are necessary. Furthermore, to prescribe appropriate antibiotic, it is recommended to perform antibiogram test for each patient before the treatment.

Cites

No record.

References

Cite

APA: Copy

GOUDARZI, MANSOUR, MOHABATI MOBAREZ, ASHRAF, NAJAR PEERAYEH, SHAHIN, & MIRZAEE, MOHSEN. (2018). Prevalence of Multidrug Resistance in Enterococcus faecium Isolated from Patients and Environment of Hospitals in Lorestan Province, (Iran). QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 12(5 ), 71-78. SID. https://sid.ir/paper/131889/en

Vancouver: Copy

GOUDARZI MANSOUR, MOHABATI MOBAREZ ASHRAF, NAJAR PEERAYEH SHAHIN, MIRZAEE MOHSEN. Prevalence of Multidrug Resistance in Enterococcus faecium Isolated from Patients and Environment of Hospitals in Lorestan Province, (Iran). QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2018;12(5 ):71-78. Available from: https://sid.ir/paper/131889/en

IEEE: Copy

MANSOUR GOUDARZI, ASHRAF MOHABATI MOBAREZ, SHAHIN NAJAR PEERAYEH, and MOHSEN MIRZAEE, “Prevalence of Multidrug Resistance in Enterococcus faecium Isolated from Patients and Environment of Hospitals in Lorestan Province, (Iran),” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 12, no. 5 , pp. 71–78, 2018, [Online]. Available: https://sid.ir/paper/131889/en

Related Journal Papers