NO EVIDENCE OF HUMAN HERPESVIRUS 8 AMONG IRANIAN PATIENTS INFECTED WITH HIV

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RAMEZANI AMITIS

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Journal Paper

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Journal: Iranian Journal of Public Health Year:2016 | Volume:45 | Issue:7 Page(s): 935-940

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Title

NO EVIDENCE OF HUMAN HERPESVIRUS 8 AMONG IRANIAN PATIENTS INFECTED WITH HIV

Author(s)

RAMEZANI AMITIS | Issue Writer Certificate

Keywords

HUMAN IMMUNODEFICIENCY VIRUS (HIV)

HUMAN HERPESVIRUS 8 (HHV-8)

PREVALENCE

VIREMIA

IRAN

Abstract

Background: Kaposi’s sarcoma is a vascular malignancy, which frequently occurs among immunocompromised indi-viduals such as transplant recipients and patients with acquired immunodeficiency syndrome. Human herpesvirus 8 (HHV-8) is considered the etiological agent of all forms of Kaposi’s sarcoma. Though some seroepidemiological stud-ies conducted on the PREVALENCE of HHV-8 in IRAN, there are insufficient data on the PREVALENCE of HHV-8 VIREMIA in HIV infected patients. We therefore, aimed to determine the PREVALENCE of HHV-8 VIREMIA in general population and HIV infected patients without Kaposi’s sarcoma in Tehran, IRAN.Methods: We conducted a cross sectional survey on 99 patients with HIV infection referred to IRANian Research Cen-ter for HIV/AIDS and 40 healthy controls in Tehran, IRAN from January to April 2014. The presence of HHV-8 DNA was detected in buffy coat samples of enrolled subjects using nested PCR assay.Results: A total of 99 HIV infected patients with mean age of 37.9±10 yr and 40 healthy controls with mean age of 39±11.5 yr were enrolled in the study. The mean CD4 count was 410.3 ± 211.4 cells/mm3. HHV-8 DNA was not de-tected in both healthy control and HIV patient groups.Conclusion: This survey showed low rate of HHV-8 DNA in healthy controls and HIV patients. Considering our findings HHV-8 infection does not seem to be widespread in our population. Further studies focusing on different regions of IRAN appear to be required to have a more accurate estimation.

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APA: Copy

RAMEZANI, AMITIS. (2016). NO EVIDENCE OF HUMAN HERPESVIRUS 8 AMONG IRANIAN PATIENTS INFECTED WITH HIV. IRANIAN JOURNAL OF PUBLIC HEALTH, 45(7), 935-940. SID. https://sid.ir/paper/274322/en

Vancouver: Copy

RAMEZANI AMITIS. NO EVIDENCE OF HUMAN HERPESVIRUS 8 AMONG IRANIAN PATIENTS INFECTED WITH HIV. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2016;45(7):935-940. Available from: https://sid.ir/paper/274322/en

IEEE: Copy

AMITIS RAMEZANI, “NO EVIDENCE OF HUMAN HERPESVIRUS 8 AMONG IRANIAN PATIENTS INFECTED WITH HIV,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 45, no. 7, pp. 935–940, 2016, [Online]. Available: https://sid.ir/paper/274322/en

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