DIOXIN EXPOSURE IN THE MANUFACTURE OF PESTICIDE PRODUCTION AS A RISK FACTOR FOR DEATH FROM PROSTATE CANCER: A META-ANALYSIS

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KABIR ALI; ZENDEHDEL REZVAN; TAYEFE RAHIMIAN RANA

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Journal: Iranian Journal of Public Health Year:2018 | Volume:47 | Issue:2 Page(s): 148-155

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Title

DIOXIN EXPOSURE IN THE MANUFACTURE OF PESTICIDE PRODUCTION AS A RISK FACTOR FOR DEATH FROM PROSTATE CANCER: A META-ANALYSIS

Author(s)

KABIR ALI | ZENDEHDEL REZVAN | TAYEFE RAHIMIAN RANA | Issue Writer Certificate

Keywords

DIOXIN

META-ANALYSIS

PESTICIDES

PROSTATIC NEOPLASM

Abstract

Background: In pesticide exposure groups such as farmers, the risk of prostate cancer was increased, although the report of the cause of evidence is limited. We selected chlorophenol compounds as an important group of the contaminated pesticide with highly toxic 2, 3, 7, 8-tetrachlorodibenzo-p-DIOXIN (TCDD). This META-ANALYSIS, the risk of death from prostate cancer was analyzed. Methods: PubMed, Scopus, Scholar Google and web of Sciences until 2016 were searched. The standardized mortality rate (SMR) and 95% confidence intervals (CI) were obtained from the studies. We tested statistical heterogeneity with Cochrane Q test and I2 index. Egger test was used for evaluating publication bias. Random or fixed-effects models and meta-regression were also used in our analysis. Moreover, Cochrane tool was used to assess the risk of bias. Results: Five available papers consist of 28706 exposed populations were assessed. Overall standardized mor-tality rate as combined result of prostate cancer risk from the fixed model was 1. 2 (95% confidence interval (CI) 1. 02 to 1. 42, P=0. 027). Some biases are more probable in these studies such as confounding by indication, loss to follow up and misclassification. Conclusion: A contaminated pesticide with DIOXINs between other PESTICIDES is an important risk factor for prostate cancers.

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APA: Copy

KABIR, ALI, ZENDEHDEL, REZVAN, & TAYEFE RAHIMIAN, RANA. (2018). DIOXIN EXPOSURE IN THE MANUFACTURE OF PESTICIDE PRODUCTION AS A RISK FACTOR FOR DEATH FROM PROSTATE CANCER: A META-ANALYSIS. IRANIAN JOURNAL OF PUBLIC HEALTH, 47(2), 148-155. SID. https://sid.ir/paper/274784/en

Vancouver: Copy

KABIR ALI, ZENDEHDEL REZVAN, TAYEFE RAHIMIAN RANA. DIOXIN EXPOSURE IN THE MANUFACTURE OF PESTICIDE PRODUCTION AS A RISK FACTOR FOR DEATH FROM PROSTATE CANCER: A META-ANALYSIS. IRANIAN JOURNAL OF PUBLIC HEALTH[Internet]. 2018;47(2):148-155. Available from: https://sid.ir/paper/274784/en

IEEE: Copy

ALI KABIR, REZVAN ZENDEHDEL, and RANA TAYEFE RAHIMIAN, “DIOXIN EXPOSURE IN THE MANUFACTURE OF PESTICIDE PRODUCTION AS A RISK FACTOR FOR DEATH FROM PROSTATE CANCER: A META-ANALYSIS,” IRANIAN JOURNAL OF PUBLIC HEALTH, vol. 47, no. 2, pp. 148–155, 2018, [Online]. Available: https://sid.ir/paper/274784/en

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