TWO BIOACTIVE FERULIC ACID DERIVATIVES FROM EREMOSTACHYS GLABRA

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SHOEB MOHAMMAD.; KUMARASAMY YASH.; NAHAR LUTFUN; MODARESI MASOUD

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Journal: DARU Journal of Pharmaceutical Sciences Year:2004 | Volume:12 | Issue:2 Page(s): 49-53

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Title

TWO BIOACTIVE FERULIC ACID DERIVATIVES FROM EREMOSTACHYS GLABRA

Author(s)

SHOEB MOHAMMAD. | KUMARASAMY YASH. | NAHAR LUTFUN | MODARESI MASOUD | Issue Writer Certificate

Keywords

EREMOSTACHYS GLABRA

LAMIACEAE

NATURAL ANTIOXIDANT

DPPH ASSAY

BRINE SHRIMP LETHALITY ASSAY

HEXACOSYL-(E)-FERULATE

LEUCOSCEPTOSIDE A

EREMOSTACHYS PULVINARIS

Abstract

Two ferulic acid derivatives, hexacosyl - (E) - ferulate [1] and LEUCOSCEPTOSIDE A [2], have been isolated from the rhizomes of EREMOSTACHYS GLABRA. The chemical structures of these compounds have been elucidated by UV, ESIMS, H~1 NMR and C~13 NMR spectroscopic analyses, and also by comparing experimental data with respective literature data. The free radical scavenging activity and general toxicity of these compounds have been assessed. While none of these compounds has shown any significant general toxicity in the BRINE SHRIMP LETHALITY ASSAY (LD__50>1 mg/mL), compounds 1 and 2 displayed significant antioxidant activity in the DPPH ASSAY (RC__50 = 0.0976 mg/mL and 0.0148 mg/mL, respectively).

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APA: Copy

SHOEB, MOHAMMAD., KUMARASAMY, YASH., NAHAR, LUTFUN, MODARESI, MASOUD,. (2004). TWO BIOACTIVE FERULIC ACID DERIVATIVES FROM EREMOSTACHYS GLABRA. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 12(2), 49-53. SID. https://sid.ir/paper/275206/en

Vancouver: Copy

SHOEB MOHAMMAD., KUMARASAMY YASH., NAHAR LUTFUN, MODARESI MASOUD. TWO BIOACTIVE FERULIC ACID DERIVATIVES FROM EREMOSTACHYS GLABRA. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2004;12(2):49-53. Available from: https://sid.ir/paper/275206/en

IEEE: Copy

MOHAMMAD. SHOEB, YASH. KUMARASAMY, LUTFUN NAHAR, MASOUD MODARESI, an, “TWO BIOACTIVE FERULIC ACID DERIVATIVES FROM EREMOSTACHYS GLABRA,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 12, no. 2, pp. 49–53, 2004, [Online]. Available: https://sid.ir/paper/275206/en

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