TOXIC PYRROLIZIDINE ALKALOIDS OF ECHIUM AMOENUM FISCH. & MEY

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MEHRABANI M.; GHANADI A.R.; SAJJADI E.; GHASSEMI N.; SHAMS ARDAKANI M.R.

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Journal Paper

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Journal: DARU Journal of Pharmaceutical Sciences Year:2006 | Volume:14 | Issue:3 Page(s): 122-127

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Title

TOXIC PYRROLIZIDINE ALKALOIDS OF ECHIUM AMOENUM FISCH. & MEY

Author(s)

Keywords

ECHIUM AMOENUM

PYRROLIZIDINE ALKALOIDS

ECHIMIDINE

ECHIMIDINE ISOMER

7-ANGELOYL RETRONECINE

7-TIGLOYL RETRONECINE

Abstract

Toxic PYRROLIZIDINE ALKALOIDS are present in some species of Echium (Boraginaceae). In this study petals of ECHIUM AMOENUM Fisch. & Mey. (Gol-e-Gavzaban) as a popular herbal medicine in Iran, were investigated for PYRROLIZIDINE ALKALOIDS (PAs). The alkaloids were separated and purified by preparative TLC and characterized by IR, one and two dimensional 1H and 13C-NMR and Mass spectroscopy. Four toxic alkaloids namely: ECHIMIDINE I, ECHIMIDINE isomer II, 7-ANGELOYL RETRONECINE III and 7-TIGLOYL RETRONECINE IV were identified.

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APA: Copy

MEHRABANI, M., GHANADI, A.R., SAJJADI, E., GHASSEMI, N., & SHAMS ARDAKANI, M.R.. (2006). TOXIC PYRROLIZIDINE ALKALOIDS OF ECHIUM AMOENUM FISCH. & MEY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 14(3), 122-127. SID. https://sid.ir/paper/275352/en

Vancouver: Copy

MEHRABANI M., GHANADI A.R., SAJJADI E., GHASSEMI N., SHAMS ARDAKANI M.R.. TOXIC PYRROLIZIDINE ALKALOIDS OF ECHIUM AMOENUM FISCH. & MEY. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2006;14(3):122-127. Available from: https://sid.ir/paper/275352/en

IEEE: Copy

M. MEHRABANI, A.R. GHANADI, E. SAJJADI, N. GHASSEMI, and M.R. SHAMS ARDAKANI, “TOXIC PYRROLIZIDINE ALKALOIDS OF ECHIUM AMOENUM FISCH. & MEY,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 14, no. 3, pp. 122–127, 2006, [Online]. Available: https://sid.ir/paper/275352/en

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