مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

650
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

399
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF 3,5- DIACETYLTAMBULIN ISOLATED FROM AMORPHOPHALLUS CAMPANULATUS BLUME EX. DECNE

Pages

  239-244

Abstract

 Background and purpose of the study: Amorphophallus campanulatus is widely distributed in Bangladesh, India, and Africa and the tuberous roots of the plant has many traditional uses and is an important source of biologically active compounds. In the present study in vitro antibacterial, antifungal and cytotoxic activities of 3,5-diacetyltambulin which is a FLAVONOID isolated from Amorphophallus campanulatus was studied. Materials and Methods: In vitro antibacterial and antifungal activities was evaluated by disc diffusion and MICs technique was determined by serial dilution technique. CYTOTOXICITY was determined against brine shrimp nauplii.Results and Major conclusion: The compound showed significant antibacterial activities against four GRAM-POSITIVE bacteria (Bacillus subtilis, Bacillus megaterium, Staphylococcus aureus, Streptococcus b-haemolyticus) and six GRAM-NEGATIVE bacteria (Escheichia coli, Shigella dysenteriae, Shigella sonnei, Shigella flexneri, Pseudomonus aeruginosa, Salmonella typhi). The MIC values against these bacteria ranged from 8 to 64 mg/ml but had weak antifungal activity against a number of fungi. In CYTOTOXICITY determination, LC50 of the compound against brine shrimp nauplii was 10.02 mg/ml

Cites

  • No record.

    • References

    Cite

    APA: Copy

    KHAN, A., RAHMAN, M., & ISLAM, M.S.. (2008). ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF 3,5- DIACETYLTAMBULIN ISOLATED FROM AMORPHOPHALLUS CAMPANULATUS BLUME EX. DECNE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE, 16(4), 239-244. SID. https://sid.ir/paper/275477/en

    Vancouver: Copy

    KHAN A., RAHMAN M., ISLAM M.S.. ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF 3,5- DIACETYLTAMBULIN ISOLATED FROM AMORPHOPHALLUS CAMPANULATUS BLUME EX. DECNE. DARU JOURNAL OF PHARMACEUTICAL SCIENCE[Internet]. 2008;16(4):239-244. Available from: https://sid.ir/paper/275477/en

    IEEE: Copy

    A. KHAN, M. RAHMAN, and M.S. ISLAM, “ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXIC ACTIVITIES OF 3,5- DIACETYLTAMBULIN ISOLATED FROM AMORPHOPHALLUS CAMPANULATUS BLUME EX. DECNE,” DARU JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 16, no. 4, pp. 239–244, 2008, [Online]. Available: https://sid.ir/paper/275477/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button