EARLY ACUTE KIDNEY INJURY BASED ON SERUM CREATININE OR CYSTATIN C IN INTENSIVE CARE UNIT AFTER MAJOR TRAUMA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAND FARID; SABETIAN GOLNAR; ABBASI GHASEM; REZAIANZADEH ABBAS; SALEHI ALIREZA; KHOSRAVI ABBAS; GERAMIZADEH BITA; TAREGH SHUJA ULHAQ; JAVADPOUR SHOHREH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS) Year:2015 | Volume:40 | Issue:6 Page(s): 485-492

Download Full-Text

View:

294

Download:

Cites:

Information Journal Paper

Title

EARLY ACUTE KIDNEY INJURY BASED ON SERUM CREATININE OR CYSTATIN C IN INTENSIVE CARE UNIT AFTER MAJOR TRAUMA

Author(s)

Keywords

ACUTE KIDNEY INJURY

TRAUMA

CYSTATIN C

CREATININE

GLOMERULAR FILTRATION RATE

Abstract

Background: ACUTE KIDNEY INJURY (AKI) is a common problem in critically ill patients and is independently associated with increased morbidity and mortality. Recently, serum CYSTATIN C has been shown to be superior to CREATININE in early detection of renal function impairment. We compared estimated GFR based on serum CYSTATIN C with estimated GFR based on serum CREATININE for early detection of renal dysfunction according to the RIFLE criteria.Methods: During 9 months, three hundred post TRAUMA patients that were referred to the intensive care unit of a referral TRAUMA hospital were recruited. Serum CREATININE and serum CYSTATIN C were measured and the estimated GFR within 24 hours of ICU admission was calculated. The primary outcome was the incidence of AKI according to the RIFLE criteria within 2nd to 7th day of admission.Results: During the first week of ICU admission, 21% of patients experienced AKI. After adjusting for major confounders, only the patients with first day’s serum cystatin level higher than 0.78 mg/l were at higher risk of first week AKI (OR=6.14, 95% CI: 2.5-14.7, P<0.001). First day’s serum CYSTATIN C and injury severity score were the major risk factors for ICU mortality (OR=3.54, 95% CI: 1.7-7.4, P=0.001) and (OR=4.6, 95% CI: 1.5-14, P=0.007), respectively.Conclusion: Within 24 hours after admission in ICU due to multiple TRAUMA, high serum CYSTATIN C level may have prognostic value in predicting early AKI and mortality during ICU admission. However, such correlation was not seen neither with CREATININE nor CYSTATIN C based GFR.

Cites

No record.

References

No record.

Cite

APA: Copy

ZAND, FARID, SABETIAN, GOLNAR, ABBASI, GHASEM, REZAIANZADEH, ABBAS, SALEHI, ALIREZA, KHOSRAVI, ABBAS, GERAMIZADEH, BITA, TAREGH, SHUJA ULHAQ, & JAVADPOUR, SHOHREH. (2015). EARLY ACUTE KIDNEY INJURY BASED ON SERUM CREATININE OR CYSTATIN C IN INTENSIVE CARE UNIT AFTER MAJOR TRAUMA. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), 40(6), 485-492. SID. https://sid.ir/paper/276517/en

Vancouver: Copy

ZAND FARID, SABETIAN GOLNAR, ABBASI GHASEM, REZAIANZADEH ABBAS, SALEHI ALIREZA, KHOSRAVI ABBAS, GERAMIZADEH BITA, TAREGH SHUJA ULHAQ, JAVADPOUR SHOHREH. EARLY ACUTE KIDNEY INJURY BASED ON SERUM CREATININE OR CYSTATIN C IN INTENSIVE CARE UNIT AFTER MAJOR TRAUMA. IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS)[Internet]. 2015;40(6):485-492. Available from: https://sid.ir/paper/276517/en

IEEE: Copy

FARID ZAND, GOLNAR SABETIAN, GHASEM ABBASI, ABBAS REZAIANZADEH, ALIREZA SALEHI, ABBAS KHOSRAVI, BITA GERAMIZADEH, SHUJA ULHAQ TAREGH, and SHOHREH JAVADPOUR, “EARLY ACUTE KIDNEY INJURY BASED ON SERUM CREATININE OR CYSTATIN C IN INTENSIVE CARE UNIT AFTER MAJOR TRAUMA,” IRANIAN JOURNAL OF MEDICAL SCIENCES (IJMS), vol. 40, no. 6, pp. 485–492, 2015, [Online]. Available: https://sid.ir/paper/276517/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops