RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE

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ARDESTANI S.K.; AMANI M.; KARIMINIA AMINA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Iranian Biomedical Journal Year:2000 | Volume:4 | Issue:1 Page(s): 51-55

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Title

RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE

Author(s)

ARDESTANI S.K. | AMANI M. | KARIMINIA AMINA | Issue Writer Certificate

Keywords

VITAMIN E

IMMUNE RESPONSE

G -IRRADIATION

BALB/C MICE

Abstract

Elevated amount of the free radicals due to ionizing radiation causes deteriorating damage on immune system. Therefore, we made attempts to investigate the protective effect of VITAMIN E (vit-E), a biological antioxidant in BALB/C MICE, so as to find an affordable prophylactic supplementation for individuals who are at risk. Several groups of mice were selected and exposed to sub-lethal G -IRRADIATION with or without vit-E supplementation. At the end of exposure, mice were immunized by either live attenuated Brucella melitensis vaccine or sheep red blood cell (SRBC). Consequently, the following parameters were assayed: specific antibody response, delayed type hypersensitivity and lymphocyte proliferation. We showed that vit-E supplementation restored the IMMUNE RESPONSE in g -irradiated mice. These findings might have implications for individuals who are at risk of exposure to ionizing radiation. Iran. Biomed.

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APA: Copy

ARDESTANI, S.K., AMANI, M., & KARIMINIA, AMINA. (2000). RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE. IRANIAN BIOMEDICAL JOURNAL, 4(1), 51-55. SID. https://sid.ir/paper/277030/en

Vancouver: Copy

ARDESTANI S.K., AMANI M., KARIMINIA AMINA. RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE. IRANIAN BIOMEDICAL JOURNAL[Internet]. 2000;4(1):51-55. Available from: https://sid.ir/paper/277030/en

IEEE: Copy

S.K. ARDESTANI, M. AMANI, and AMINA KARIMINIA, “RESTORATIVE EFFECT OF VITAMIN E ON SOME IMMUNOLOGICAL PARAMETERS OF SUB-LETHAL G -IRRADIATED BALB/C MICE,” IRANIAN BIOMEDICAL JOURNAL, vol. 4, no. 1, pp. 51–55, 2000, [Online]. Available: https://sid.ir/paper/277030/en

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