DNA FRAGMENTATION IS NOT ASSOCIATED WITH APOPTOSIS IN ZERUMBONE-INDUCED HEPG2 CELLS (LETTER TO THE EDITOR) (LETTER TO THE EDITOR)

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KAMALIDEHGHAN BEHNAM; AHMADIPOUR FATEMEH; NOORDIN MOHAMED IBRAHIM

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Journal: Iranian Biomedical Journal Year:2012 | Volume:16 | Issue:4 Page(s): 226-226

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Title

DNA FRAGMENTATION IS NOT ASSOCIATED WITH APOPTOSIS IN ZERUMBONE-INDUCED HEPG2 CELLS (LETTER TO THE EDITOR) (LETTER TO THE EDITOR)

Author(s)

KAMALIDEHGHAN BEHNAM | AHMADIPOUR FATEMEH | NOORDIN MOHAMED IBRAHIM | Issue Writer Certificate

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Abstract

zerumbone is a cytotoxic compound isolated from the herbal plant, Zingiber zerumbet Smith, which exhibits antitumor activity [1-2], anti-inflammatory effects and possesses anti-proliferative potentials in a variety of cell lines [3-4].DNA fragmentation indicates an early event of apoptosis leading to cell death due to the absence of new cellular proteins synthesizing for cell survival. Previous studies indicated that the cleavage of doublestranded DNA in apoptotic DNA degradation occurs via the activation of endogenous Ca2+/Mg2+-dependent endonuclease that specifically cleaves between nucleosomes to produce DNA fragments that are multiples of ~180 base pairs [5].

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APA: Copy

KAMALIDEHGHAN, BEHNAM, AHMADIPOUR, FATEMEH, & NOORDIN, MOHAMED IBRAHIM. (2012). DNA FRAGMENTATION IS NOT ASSOCIATED WITH APOPTOSIS IN ZERUMBONE-INDUCED HEPG2 CELLS (LETTER TO THE EDITOR) (LETTER TO THE EDITOR). IRANIAN BIOMEDICAL JOURNAL, 16(4), 226-226. SID. https://sid.ir/paper/277418/en

Vancouver: Copy

KAMALIDEHGHAN BEHNAM, AHMADIPOUR FATEMEH, NOORDIN MOHAMED IBRAHIM. DNA FRAGMENTATION IS NOT ASSOCIATED WITH APOPTOSIS IN ZERUMBONE-INDUCED HEPG2 CELLS (LETTER TO THE EDITOR) (LETTER TO THE EDITOR). IRANIAN BIOMEDICAL JOURNAL[Internet]. 2012;16(4):226-226. Available from: https://sid.ir/paper/277418/en

IEEE: Copy

BEHNAM KAMALIDEHGHAN, FATEMEH AHMADIPOUR, and MOHAMED IBRAHIM NOORDIN, “DNA FRAGMENTATION IS NOT ASSOCIATED WITH APOPTOSIS IN ZERUMBONE-INDUCED HEPG2 CELLS (LETTER TO THE EDITOR) (LETTER TO THE EDITOR),” IRANIAN BIOMEDICAL JOURNAL, vol. 16, no. 4, pp. 226–226, 2012, [Online]. Available: https://sid.ir/paper/277418/en

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