MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NOURI DALOUEI M.R.; DANESH PAZHOUH MARYAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ACTA MEDICA IRANICA Year:2008 | Volume:46 | Issue:3 Page(s): 167-182

Download Full-Text

View:

457

Download:

294

Cites:

Information Journal Paper

Title

MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE

Author(s)

NOURI DALOUEI M.R. | DANESH PAZHOUH MARYAM | Issue Writer Certificate

Keywords

GLUCOSE-6-PHOSPHATE DEHYDROGENASE

HEMOLYSIS

SENESCENCE

FAVISM

GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY

Abstract

GLUCOSE-6-PHOSPHATE DEHYDROGENASE is an essential enzyme to cell growth. Its deficiency of enzyme plays an important role in SENESCENCE and death signaling. Also, it is actually the most common clinically important enzyme defect, not only in hematology, but also among all human known diseases. Clinical consequences of enzyme deficiency are: neonatal hyperbilirubinemia, acute hemolytic anemia, and chronic hemolytic anemia. The enzyme gene spans 18 kb on the X chromosome (xq28) and contains 13 exons. Its promoter is embedded in a CpG island that is conserved from mice to humans. The development of a number of PCR-based methods for the detection of known mutations in GLUCOSE-6-PHOSPHATE DEHYDROGENASE has made it possible to detect enzyme deficiency and identify the specific mutation responsible with relative ease. We will discuss the mentioned clinical manifestations of GLUCOSE-6-PHOSPHATE DEHYDROGENASE deficiency, Genetics, biochemistry and pathophysiology of the enzyme in details using newer published data and present most of the studies in Iranian population.

Cites

No record.

References

No record.

Cite

APA: Copy

NOURI DALOUEI, M.R., & DANESH PAZHOUH, MARYAM. (2008). MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE. ACTA MEDICA IRANICA, 46(3), 167-182. SID. https://sid.ir/paper/278118/en

Vancouver: Copy

NOURI DALOUEI M.R., DANESH PAZHOUH MARYAM. MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE. ACTA MEDICA IRANICA[Internet]. 2008;46(3):167-182. Available from: https://sid.ir/paper/278118/en

IEEE: Copy

M.R. NOURI DALOUEI, and MARYAM DANESH PAZHOUH, “MOLECULAR BASIS OF G6PD DEFICIENCY: CURRENT STATUS AND ITS PERSPECTIVE,” ACTA MEDICA IRANICA, vol. 46, no. 3, pp. 167–182, 2008, [Online]. Available: https://sid.ir/paper/278118/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops