THE EFFECT OF ALPHA-LIPOIC ACID ON BLOOD PRESSURE IN TYPE 2 DIABETICS

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MAZLOUM ZOHREH; ANSAR HASTI

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Paper Information

Journal: Iranian Journal of Endocrinology & Metabolism Year:2009 | Volume:11 | Issue:3 (SN 45) Page(s): 245-250

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Information Journal Paper

Title

THE EFFECT OF ALPHA-LIPOIC ACID ON BLOOD PRESSURE IN TYPE 2 DIABETICS

Author(s)

MAZLOUM ZOHREH | ANSAR HASTI | Issue Writer Certificate

Keywords

ALPHA-LIPOIC ACIDQ3

TYPE 2 DIABETESQ2

BLOOD PRESSUREQ3

OXIDATIVE STRESSQ2

ANTIOXIDANTQ2

Abstract

Introduction: Majority of diabetic patients eventually develop hypertension. Becase of its antioxidative properties, ALPHA-LIPOIC ACID plays an effective role in decreasing OXIDATIVE STRESS and preventing endothelium dysfunction. The purpose of the present study was to determine the effect of ALPHA-LIPOIC ACID on BLOOD PRESSURE in type 2 diabetic patients. Materials & Methods: Fifty-seven type 2 diabetic patients (14 male and 43 female), mean age 53.5 years, were enrolled in this study. Upon arrival subjects were randomly divided into either the experimental (n=29) or control (n=28) groups. The experimental group received 300 mg ALPHA-LIPOIC ACID daily for eight weeks, while the control group received a placebo for eight weeks. BLOOD PRESSURE and 24 hours diet recall were measured at the beginning of the study and every two weeks after that. Results: The results of the study showed a significant decrease in both systolic and diastolic BLOOD PRESSUREs at the end of study in the alpha lipoic acid group compared to their initial values (p<0/0001), and to the control group (p=0/001). Conclusion: This study suggests that ALPHA-LIPOIC ACID supplements can be recommended for type 2 diabetic patients to prevent high BLOOD PRESSURE.

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APA: Copy

MAZLOUM, ZOHREH, & ANSAR, HASTI. (2009). THE EFFECT OF ALPHA-LIPOIC ACID ON BLOOD PRESSURE IN TYPE 2 DIABETICS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 11(3 (SN 45)), 245-250. SID. https://sid.ir/paper/27880/en

Vancouver: Copy

MAZLOUM ZOHREH, ANSAR HASTI. THE EFFECT OF ALPHA-LIPOIC ACID ON BLOOD PRESSURE IN TYPE 2 DIABETICS. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2009;11(3 (SN 45)):245-250. Available from: https://sid.ir/paper/27880/en

IEEE: Copy

ZOHREH MAZLOUM, and HASTI ANSAR, “THE EFFECT OF ALPHA-LIPOIC ACID ON BLOOD PRESSURE IN TYPE 2 DIABETICS,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 11, no. 3 (SN 45), pp. 245–250, 2009, [Online]. Available: https://sid.ir/paper/27880/en

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