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Information Journal Paper

Title

First Cystic Fibrosis Patient Registry Annual Data Report-Cystic Fibrosis Foundation of Iran

Pages

  33-41

Abstract

 Cystic fibrosis (CF), as a fatal genetic condition, is associated with high morbidity and mortality rates. In Iran, limited studies exist on this disease. This study aimed to compare the demographic, clinical and paraclinical data of CF patients. This cross-sectional study was conducted in 2014-2015 on 174 CF patients referred to the Tehran Children Medical Center hospital, which is the main referral center for CF. For each patient, the forced expiratory volume in one second (FEV1) was measured, and the comparative demographic, clinical, and laboratory data of patients were recorded. Overall, 59% of studied patients were boys (n=102) and 41% were girls (n=72). The mean patient age (and standard deviations) was 7. 1± 5. 7 years, with a range of 10 days to 28 years. In 67% of cases, the disease was diagnosed before their first birthday. The patients in this study were classified based on the FEV1 into mild (62%), moderate (33%) and severe (5%), indicating the degree of pulmonary complications. Cultures of respiratory secretions were positive for Pseudomonas aeruginosa and Staphylococcus aureus, in 23% and 16% of cases, respectively. In total, 61% of patients (n=83) were assigned to receive oral azithromycin for prophylaxis. Gastroesophageal reflux (reflux) was the most common gastrointestinal complication (35%). Regarding the complex nature of CF and the necessity of constant monitoring of patients during the life-span, the comparative demographic, clinical and laboratory analysis of patients and registering and standardization of patients’ data can be a major step in the better understanding of the disease, and thereby increasing the quality of life and life expectancy in the affected population.

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    • Cite

    APA: Copy

    AGHAMOHAMMADI, ASGHAR, Navaei, Safoura, Shirzadi, Rohola, Masiha, Farzad, ALLAMEH, ZAHRA, HEYDARI, AMIN, Eslami, Solat, AZIZI, GHOLAMREZA, & MODARESI, MOHAMMADREZA. (2019). First Cystic Fibrosis Patient Registry Annual Data Report-Cystic Fibrosis Foundation of Iran. ACTA MEDICA IRANICA, 57(1), 33-41. SID. https://sid.ir/paper/278995/en

    Vancouver: Copy

    AGHAMOHAMMADI ASGHAR, Navaei Safoura, Shirzadi Rohola, Masiha Farzad, ALLAMEH ZAHRA, HEYDARI AMIN, Eslami Solat, AZIZI GHOLAMREZA, MODARESI MOHAMMADREZA. First Cystic Fibrosis Patient Registry Annual Data Report-Cystic Fibrosis Foundation of Iran. ACTA MEDICA IRANICA[Internet]. 2019;57(1):33-41. Available from: https://sid.ir/paper/278995/en

    IEEE: Copy

    ASGHAR AGHAMOHAMMADI, Safoura Navaei, Rohola Shirzadi, Farzad Masiha, ZAHRA ALLAMEH, AMIN HEYDARI, Solat Eslami, GHOLAMREZA AZIZI, and MOHAMMADREZA MODARESI, “First Cystic Fibrosis Patient Registry Annual Data Report-Cystic Fibrosis Foundation of Iran,” ACTA MEDICA IRANICA, vol. 57, no. 1, pp. 33–41, 2019, [Online]. Available: https://sid.ir/paper/278995/en

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